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Neuron Derived Orphan Receptor 1 (NOR1)

NR4A3; NR4-A3; CHN; TEC; CSMF; MINOR; NOR1; Nuclear Receptor Subfamily 4,Group A,Member 3; Mitogen-induced nuclear orphan receptor; Nuclear hormone receptor NOR-1

The Neuron-derived orphan receptor 1 (NOR1) a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Four transcript variants encoding three distinct isoforms have been identified for this gene.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU177Hu01 Recombinant Neuron Derived Orphan Receptor 1 (NOR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU177Hu01 Monoclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IP.
PAU177Hu01 Polyclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IF.
Assay Kits CLU177Hu01 CLIA Kit for Neuron Derived Orphan Receptor 1 (NOR1) CLIA assay for Antigen Detection
ELU177Hu01 ELISA Kit for Neuron Derived Orphan Receptor 1 (NOR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU177Mu01 Recombinant Neuron Derived Orphan Receptor 1 (NOR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU177Mu01 Monoclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IP.
PAU177Mu01 Polyclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IF.
Assay Kits CLU177Mu01 CLIA Kit for Neuron Derived Orphan Receptor 1 (NOR1) CLIA assay for Antigen Detection
ELU177Mu01 ELISA Kit for Neuron Derived Orphan Receptor 1 (NOR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU177Ra01 Recombinant Neuron Derived Orphan Receptor 1 (NOR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU177Ra01 Monoclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IP.
PAU177Ra01 Polyclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IF.
Assay Kits CLU177Ra01 CLIA Kit for Neuron Derived Orphan Receptor 1 (NOR1) CLIA assay for Antigen Detection
ELU177Ra01 ELISA Kit for Neuron Derived Orphan Receptor 1 (NOR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU177Ca01 Recombinant Neuron Derived Orphan Receptor 1 (NOR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU177Ca01 Monoclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IP.
PAU177Ca01 Polyclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IF.
Assay Kits CLU177Ca01 CLIA Kit for Neuron Derived Orphan Receptor 1 (NOR1) CLIA assay for Antigen Detection
ELU177Ca01 ELISA Kit for Neuron Derived Orphan Receptor 1 (NOR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU177Po01 Recombinant Neuron Derived Orphan Receptor 1 (NOR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU177Po01 Monoclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IP.
PAU177Po01 Polyclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IF.
Assay Kits CLU177Po01 CLIA Kit for Neuron Derived Orphan Receptor 1 (NOR1) CLIA assay for Antigen Detection
ELU177Po01 ELISA Kit for Neuron Derived Orphan Receptor 1 (NOR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU177Bo01 Recombinant Neuron Derived Orphan Receptor 1 (NOR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU177Bo01 Monoclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IP.
PAU177Bo01 Polyclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IF.
Assay Kits CLU177Bo01 CLIA Kit for Neuron Derived Orphan Receptor 1 (NOR1) CLIA assay for Antigen Detection
ELU177Bo01 ELISA Kit for Neuron Derived Orphan Receptor 1 (NOR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU177Rb01 Recombinant Neuron Derived Orphan Receptor 1 (NOR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU177Rb01 Monoclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IP.
PAU177Rb01 Polyclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IF.
Assay Kits CLU177Rb01 CLIA Kit for Neuron Derived Orphan Receptor 1 (NOR1) CLIA assay for Antigen Detection
ELU177Rb01 ELISA Kit for Neuron Derived Orphan Receptor 1 (NOR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU177Mo01 Recombinant Neuron Derived Orphan Receptor 1 (NOR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU177Mo01 Monoclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IP.
PAU177Mo01 Polyclonal Antibody to Neuron Derived Orphan Receptor 1 (NOR1) WB; IHC; ICC; IF.
Assay Kits CLU177Mo01 CLIA Kit for Neuron Derived Orphan Receptor 1 (NOR1) CLIA assay for Antigen Detection
ELU177Mo01 ELISA Kit for Neuron Derived Orphan Receptor 1 (NOR1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Structure, mapping and expression of a human NOR-1 gene, the third member of the Nur77/NGFI-B family."
Biochim. Biophys. Acta 1308:205-214(1996) [PubMed] [Europe PMC] [Abstract]

"The isolation and characterization of MINOR, a novel mitogen-inducible nuclear orphan receptor."
Mol. Endocrinol. 9:1692-1700(1995) [PubMed] [Europe PMC] [Abstract]

"Fusion of the EWS gene to CHN, a member of the steroid/thyroid receptor gene superfamily, in a human myxoid chondrosarcoma."
Oncogene 12:229-235(1996) [PubMed] [Europe PMC] [Abstract]

"Oncogenic conversion of a novel orphan nuclear receptor by chromosome translocation."
Hum. Mol. Genet. 4:2219-2226(1995) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 9."
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]

"Alternative splicing generates isoforms of human neuron-derived orphan receptor-1 (NOR-1) mRNA."
Gene 211:79-85(1998) [PubMed] [Europe PMC] [Abstract]

"The homeotic protein Six3 is a coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas."
Cancer Res. 63:449-454(2003) [PubMed] [Europe PMC] [Abstract]