Perilipin 1 (PLIN1)
PERI; PLIN1; Lipid Droplet Associated Protein
Perilipin is a protein that coats lipid droplets in adipocytes, the fat-storing cells in adipose tissue. Perilipin acts as a protective coating from the body’s natural lipases, such as hormone-sensitive lipase,which break triglycerides into glycerol and free fatty acids for use in metabolism, a process called lipolysis.
Perilipin is hyperphosphorylated by PKA following β-adrenergic receptor activation. Phosphorylated perilipin changes conformation, exposing the stored lipids to hormone-sensitive lipase-mediated lipolysis. Although PKA also phosphorylates hormone-sensitive lipase, which can increase PKA activity, the more than 50-fold increase in fat mobilization (triggered by epinephrine) is primarily due to perilipin phosphorylation.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU112Hu01 | Recombinant Perilipin 1 (PLIN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU112Hu01 | Monoclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IP. |
| PAU112Hu01 | Polyclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU112Hu01 | CLIA Kit for Perilipin 1 (PLIN1) | CLIA assay for Antigen Detection |
| ELU112Hu01 | ELISA Kit for Perilipin 1 (PLIN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU112Mu01 | Recombinant Perilipin 1 (PLIN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU112Mu01 | Monoclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IP. |
| PAU112Mu01 | Polyclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU112Mu01 | CLIA Kit for Perilipin 1 (PLIN1) | CLIA assay for Antigen Detection |
| ELU112Mu01 | ELISA Kit for Perilipin 1 (PLIN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU112Ra01 | Recombinant Perilipin 1 (PLIN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU112Ra01 | Monoclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IP. |
| PAU112Ra01 | Polyclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU112Ra01 | CLIA Kit for Perilipin 1 (PLIN1) | CLIA assay for Antigen Detection |
| ELU112Ra01 | ELISA Kit for Perilipin 1 (PLIN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU112Ca01 | Recombinant Perilipin 1 (PLIN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU112Ca01 | Monoclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IP. |
| PAU112Ca01 | Polyclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU112Ca01 | CLIA Kit for Perilipin 1 (PLIN1) | CLIA assay for Antigen Detection |
| ELU112Ca01 | ELISA Kit for Perilipin 1 (PLIN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU112Po01 | Recombinant Perilipin 1 (PLIN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU112Po01 | Monoclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IP. |
| PAU112Po01 | Polyclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU112Po01 | CLIA Kit for Perilipin 1 (PLIN1) | CLIA assay for Antigen Detection |
| ELU112Po01 | ELISA Kit for Perilipin 1 (PLIN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU112Bo01 | Recombinant Perilipin 1 (PLIN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU112Bo01 | Monoclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IP. |
| PAU112Bo01 | Polyclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU112Bo01 | CLIA Kit for Perilipin 1 (PLIN1) | CLIA assay for Antigen Detection |
| ELU112Bo01 | ELISA Kit for Perilipin 1 (PLIN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU112Rb01 | Recombinant Perilipin 1 (PLIN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU112Rb01 | Monoclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IP. |
| PAU112Rb01 | Polyclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU112Rb01 | CLIA Kit for Perilipin 1 (PLIN1) | CLIA assay for Antigen Detection |
| ELU112Rb01 | ELISA Kit for Perilipin 1 (PLIN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU112Mo01 | Recombinant Perilipin 1 (PLIN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU112Mo01 | Monoclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IP. |
| PAU112Mo01 | Polyclonal Antibody to Perilipin 1 (PLIN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU112Mo01 | CLIA Kit for Perilipin 1 (PLIN1) | CLIA assay for Antigen Detection |
| ELU112Mo01 | ELISA Kit for Perilipin 1 (PLIN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Isolation and chromosomal mapping of the human homolog of perilipin (PLIN), a rat adipose tissue-specific gene, by differential display method."
Genomics 48:254-257(1998) [PubMed] [Europe PMC] [Abstract]
"Analysis of the DNA sequence and duplication history of human chromosome 15."
Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Perilipin deficiency and autosomal dominant partial lipodystrophy."
N. Engl. J. Med. 364:740-748(2011) [PubMed] [Europe PMC] [Abstract]
"FSP27 and PLIN1 interaction promotes the formation of large lipid droplets in human adipocytes."
Biochem. Biophys. Res. Commun. 432:296-301(2013) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]