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Testis Specific Kinase 1 (TESK1)

Dual Specificity Testis-Specific Protein Kinase 1

Dual specificity testis-specific protein kinase 1 is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs).
The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis.Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU068Hu01 Recombinant Testis Specific Kinase 1 (TESK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU068Hu01 Monoclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IP.
PAU068Hu01 Polyclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IF.
Assay Kits CLU068Hu01 CLIA Kit for Testis Specific Kinase 1 (TESK1) CLIA assay for Antigen Detection
ELU068Hu01 ELISA Kit for Testis Specific Kinase 1 (TESK1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU068Mu01 Recombinant Testis Specific Kinase 1 (TESK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU068Mu01 Monoclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IP.
PAU068Mu01 Polyclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IF.
Assay Kits CLU068Mu01 CLIA Kit for Testis Specific Kinase 1 (TESK1) CLIA assay for Antigen Detection
ELU068Mu01 ELISA Kit for Testis Specific Kinase 1 (TESK1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU068Ra01 Recombinant Testis Specific Kinase 1 (TESK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU068Ra01 Monoclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IP.
PAU068Ra01 Polyclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IF.
Assay Kits CLU068Ra01 CLIA Kit for Testis Specific Kinase 1 (TESK1) CLIA assay for Antigen Detection
ELU068Ra01 ELISA Kit for Testis Specific Kinase 1 (TESK1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU068Ca01 Recombinant Testis Specific Kinase 1 (TESK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU068Ca01 Monoclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IP.
PAU068Ca01 Polyclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IF.
Assay Kits CLU068Ca01 CLIA Kit for Testis Specific Kinase 1 (TESK1) CLIA assay for Antigen Detection
ELU068Ca01 ELISA Kit for Testis Specific Kinase 1 (TESK1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU068Po01 Recombinant Testis Specific Kinase 1 (TESK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU068Po01 Monoclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IP.
PAU068Po01 Polyclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IF.
Assay Kits CLU068Po01 CLIA Kit for Testis Specific Kinase 1 (TESK1) CLIA assay for Antigen Detection
ELU068Po01 ELISA Kit for Testis Specific Kinase 1 (TESK1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU068Bo01 Recombinant Testis Specific Kinase 1 (TESK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU068Bo01 Monoclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IP.
PAU068Bo01 Polyclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IF.
Assay Kits CLU068Bo01 CLIA Kit for Testis Specific Kinase 1 (TESK1) CLIA assay for Antigen Detection
ELU068Bo01 ELISA Kit for Testis Specific Kinase 1 (TESK1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU068Rb01 Recombinant Testis Specific Kinase 1 (TESK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU068Rb01 Monoclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IP.
PAU068Rb01 Polyclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IF.
Assay Kits CLU068Rb01 CLIA Kit for Testis Specific Kinase 1 (TESK1) CLIA assay for Antigen Detection
ELU068Rb01 ELISA Kit for Testis Specific Kinase 1 (TESK1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU068Mo01 Recombinant Testis Specific Kinase 1 (TESK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU068Mo01 Monoclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IP.
PAU068Mo01 Polyclonal Antibody to Testis Specific Kinase 1 (TESK1) WB; IHC; ICC; IF.
Assay Kits CLU068Mo01 CLIA Kit for Testis Specific Kinase 1 (TESK1) CLIA assay for Antigen Detection
ELU068Mo01 ELISA Kit for Testis Specific Kinase 1 (TESK1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Identification and characterization of a novel protein kinase, TESK1, specifically expressed in testicular germ cells."
J. Biol. Chem. 270:31331-31337(1995) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 9."
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1."
Eur. J. Biochem. 269:2546-2556(2002) [PubMed] [Europe PMC] [Abstract]

"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

"Patterns of somatic mutation in human cancer genomes."
Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]