Transmembrane Protein 1 (TMEM1)
EHOC1; TRAPPC10; TRS130; Trafficking Protein Particle Complex Subunit 10; Epilepsy holoprosencephaly candidate 1 protein; Transport protein particle subunit TMEM1
TMEM1is a transmembrane protein found in the cis-Golgi complex. The encoded protein is part of the multisubunit transport protein particle (TRAPP) complex and may be involved in vesicular transport from the endoplasmic reticulum to the Golgi. Mutations in this gene could be responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy, or for autoimmune polyglandular disease type 1. This gene mapped less than 45 kb centromeric of D21S25 and spanned at least 56 kb of genomic DNA. Northern blot analysis revealed that 8-, 7.5-, and 5.3-kb transcripts are ubiquitously expressed in adult tissues. DNA sequence analysis showed a complete coding sequence of 3,570 bp with multiple putative transmembrane domains that shared partial homology with transmembrane proteins including sodium channel proteins.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU063Hu01 | Recombinant Transmembrane Protein 1 (TMEM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU063Hu01 | Monoclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IP. |
| PAU063Hu01 | Polyclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU063Hu01 | CLIA Kit for Transmembrane Protein 1 (TMEM1) | CLIA assay for Antigen Detection |
| ELU063Hu01 | ELISA Kit for Transmembrane Protein 1 (TMEM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU063Mu01 | Recombinant Transmembrane Protein 1 (TMEM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU063Mu01 | Monoclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IP. |
| PAU063Mu01 | Polyclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU063Mu01 | CLIA Kit for Transmembrane Protein 1 (TMEM1) | CLIA assay for Antigen Detection |
| ELU063Mu01 | ELISA Kit for Transmembrane Protein 1 (TMEM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU063Ra01 | Recombinant Transmembrane Protein 1 (TMEM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU063Ra01 | Monoclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IP. |
| PAU063Ra01 | Polyclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU063Ra01 | CLIA Kit for Transmembrane Protein 1 (TMEM1) | CLIA assay for Antigen Detection |
| ELU063Ra01 | ELISA Kit for Transmembrane Protein 1 (TMEM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU063Ca01 | Recombinant Transmembrane Protein 1 (TMEM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU063Ca01 | Monoclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IP. |
| PAU063Ca01 | Polyclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU063Ca01 | CLIA Kit for Transmembrane Protein 1 (TMEM1) | CLIA assay for Antigen Detection |
| ELU063Ca01 | ELISA Kit for Transmembrane Protein 1 (TMEM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU063Po01 | Recombinant Transmembrane Protein 1 (TMEM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU063Po01 | Monoclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IP. |
| PAU063Po01 | Polyclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU063Po01 | CLIA Kit for Transmembrane Protein 1 (TMEM1) | CLIA assay for Antigen Detection |
| ELU063Po01 | ELISA Kit for Transmembrane Protein 1 (TMEM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU063Bo01 | Recombinant Transmembrane Protein 1 (TMEM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU063Bo01 | Monoclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IP. |
| PAU063Bo01 | Polyclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU063Bo01 | CLIA Kit for Transmembrane Protein 1 (TMEM1) | CLIA assay for Antigen Detection |
| ELU063Bo01 | ELISA Kit for Transmembrane Protein 1 (TMEM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU063Rb01 | Recombinant Transmembrane Protein 1 (TMEM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU063Rb01 | Monoclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IP. |
| PAU063Rb01 | Polyclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU063Rb01 | CLIA Kit for Transmembrane Protein 1 (TMEM1) | CLIA assay for Antigen Detection |
| ELU063Rb01 | ELISA Kit for Transmembrane Protein 1 (TMEM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU063Mo01 | Recombinant Transmembrane Protein 1 (TMEM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU063Mo01 | Monoclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IP. |
| PAU063Mo01 | Polyclonal Antibody to Transmembrane Protein 1 (TMEM1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU063Mo01 | CLIA Kit for Transmembrane Protein 1 (TMEM1) | CLIA assay for Antigen Detection |
| ELU063Mo01 | ELISA Kit for Transmembrane Protein 1 (TMEM1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Isolation and characterization of a candidate gene for progressive myoclonus epilepsy on 21q22.3."
Hum. Mol. Genet. 4:709-716(1995) [PubMed] [Europe PMC] [Abstract]
"Genomic organization and complete nucleotide sequence of the TMEM1 gene on human chromosome 21q22.3."
Biochem. Biophys. Res. Commun. 235:185-190(1997) [PubMed] [Europe PMC] [Abstract]
"Genomic structure of the human GT334 (EHOC-1) gene mapping to 21q22.3."
Gene 198:313-321(1997) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of human chromosome 21."
Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Functional organization of the yeast proteome by systematic analysis of protein complexes."
Nature 415:141-147(2002) [PubMed] [Europe PMC] [Abstract]
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
"C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking."
Mol. Biol. Cell 22:2083-2093(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]