Transcriptional Regulating Factor 1 (TRERF1)
BCAR2; TREP132; RAPA; Breast Cancer Anti-Estrogen Resistance 2; Transcriptional-regulating protein 132; Zinc finger protein rapa; Zinc finger transcription factor TReP-132
Transcriptional-regulating factor 1 is a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1.The deduced 1,200-amino acid protein contains a glutamine-rich region, 2 proline-rich regions, an acidic region, and 3 C2H2-type zinc finger motifs. An alternatively spliced transcript with a longer 3-prime UTR encodes the same protein. Northern blot analysis detected transcripts of 4.4 and 7.5 kb abundantly expressed in thymus, testis, adrenal cortex, and a human choriocarcinoma cell line. Weak expression was detected in all other tissues examined except pancreas and small intestine. In vitro transcription and translation resulted in a protein with an apparent molecular mass of about 132 kD, in agreement with the predicted size.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU048Hu01 | Recombinant Transcriptional Regulating Factor 1 (TRERF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU048Hu01 | Monoclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IP. |
| PAU048Hu01 | Polyclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU048Hu01 | CLIA Kit for Transcriptional Regulating Factor 1 (TRERF1) | CLIA assay for Antigen Detection |
| ELU048Hu01 | ELISA Kit for Transcriptional Regulating Factor 1 (TRERF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU048Mu01 | Recombinant Transcriptional Regulating Factor 1 (TRERF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU048Mu01 | Monoclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IP. |
| PAU048Mu01 | Polyclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU048Mu01 | CLIA Kit for Transcriptional Regulating Factor 1 (TRERF1) | CLIA assay for Antigen Detection |
| ELU048Mu01 | ELISA Kit for Transcriptional Regulating Factor 1 (TRERF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU048Ra01 | Recombinant Transcriptional Regulating Factor 1 (TRERF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU048Ra01 | Monoclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IP. |
| PAU048Ra01 | Polyclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU048Ra01 | CLIA Kit for Transcriptional Regulating Factor 1 (TRERF1) | CLIA assay for Antigen Detection |
| ELU048Ra01 | ELISA Kit for Transcriptional Regulating Factor 1 (TRERF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU048Ca01 | Recombinant Transcriptional Regulating Factor 1 (TRERF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU048Ca01 | Monoclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IP. |
| PAU048Ca01 | Polyclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU048Ca01 | CLIA Kit for Transcriptional Regulating Factor 1 (TRERF1) | CLIA assay for Antigen Detection |
| ELU048Ca01 | ELISA Kit for Transcriptional Regulating Factor 1 (TRERF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU048Po01 | Recombinant Transcriptional Regulating Factor 1 (TRERF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU048Po01 | Monoclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IP. |
| PAU048Po01 | Polyclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU048Po01 | CLIA Kit for Transcriptional Regulating Factor 1 (TRERF1) | CLIA assay for Antigen Detection |
| ELU048Po01 | ELISA Kit for Transcriptional Regulating Factor 1 (TRERF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU048Bo01 | Recombinant Transcriptional Regulating Factor 1 (TRERF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU048Bo01 | Monoclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IP. |
| PAU048Bo01 | Polyclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU048Bo01 | CLIA Kit for Transcriptional Regulating Factor 1 (TRERF1) | CLIA assay for Antigen Detection |
| ELU048Bo01 | ELISA Kit for Transcriptional Regulating Factor 1 (TRERF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU048Rb01 | Recombinant Transcriptional Regulating Factor 1 (TRERF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU048Rb01 | Monoclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IP. |
| PAU048Rb01 | Polyclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU048Rb01 | CLIA Kit for Transcriptional Regulating Factor 1 (TRERF1) | CLIA assay for Antigen Detection |
| ELU048Rb01 | ELISA Kit for Transcriptional Regulating Factor 1 (TRERF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU048Mo01 | Recombinant Transcriptional Regulating Factor 1 (TRERF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU048Mo01 | Monoclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IP. |
| PAU048Mo01 | Polyclonal Antibody to Transcriptional Regulating Factor 1 (TRERF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU048Mo01 | CLIA Kit for Transcriptional Regulating Factor 1 (TRERF1) | CLIA assay for Antigen Detection |
| ELU048Mo01 | ELISA Kit for Transcriptional Regulating Factor 1 (TRERF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression."
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Breast Cancer Res. Treat. 114:23-30(2009) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"Direct binding of TReP-132 with TdT results in reduction of TdT activity."
Genes Cells 11:47-57(2006) [PubMed] [Europe PMC] [Abstract]
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Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
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Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]