Stanniocalcin 1 (STC1)
Stanniocalcin-1 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues.
The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT983Hu01 | Recombinant Stanniocalcin 1 (STC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT983Hu01 | Monoclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IP. |
| PAT983Hu01 | Polyclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT983Hu01 | CLIA Kit for Stanniocalcin 1 (STC1) | CLIA assay for Antigen Detection |
| ELT983Hu01 | ELISA Kit for Stanniocalcin 1 (STC1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT983Mu01 | Recombinant Stanniocalcin 1 (STC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT983Mu01 | Monoclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IP. |
| PAT983Mu01 | Polyclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT983Mu01 | CLIA Kit for Stanniocalcin 1 (STC1) | CLIA assay for Antigen Detection |
| ELT983Mu01 | ELISA Kit for Stanniocalcin 1 (STC1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT983Ra01 | Recombinant Stanniocalcin 1 (STC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT983Ra01 | Monoclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IP. |
| PAT983Ra01 | Polyclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT983Ra01 | CLIA Kit for Stanniocalcin 1 (STC1) | CLIA assay for Antigen Detection |
| ELT983Ra01 | ELISA Kit for Stanniocalcin 1 (STC1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT983Ca01 | Recombinant Stanniocalcin 1 (STC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT983Ca01 | Monoclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IP. |
| PAT983Ca01 | Polyclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT983Ca01 | CLIA Kit for Stanniocalcin 1 (STC1) | CLIA assay for Antigen Detection |
| ELT983Ca01 | ELISA Kit for Stanniocalcin 1 (STC1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT983Po01 | Recombinant Stanniocalcin 1 (STC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT983Po01 | Monoclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IP. |
| PAT983Po01 | Polyclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT983Po01 | CLIA Kit for Stanniocalcin 1 (STC1) | CLIA assay for Antigen Detection |
| ELT983Po01 | ELISA Kit for Stanniocalcin 1 (STC1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT983Bo01 | Recombinant Stanniocalcin 1 (STC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT983Bo01 | Monoclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IP. |
| PAT983Bo01 | Polyclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT983Bo01 | CLIA Kit for Stanniocalcin 1 (STC1) | CLIA assay for Antigen Detection |
| ELT983Bo01 | ELISA Kit for Stanniocalcin 1 (STC1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT983Rb01 | Recombinant Stanniocalcin 1 (STC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT983Rb01 | Monoclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IP. |
| PAT983Rb01 | Polyclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT983Rb01 | CLIA Kit for Stanniocalcin 1 (STC1) | CLIA assay for Antigen Detection |
| ELT983Rb01 | ELISA Kit for Stanniocalcin 1 (STC1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT983Mo01 | Recombinant Stanniocalcin 1 (STC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT983Mo01 | Monoclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IP. |
| PAT983Mo01 | Polyclonal Antibody to Stanniocalcin 1 (STC1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT983Mo01 | CLIA Kit for Stanniocalcin 1 (STC1) | CLIA assay for Antigen Detection |
| ELT983Mo01 | ELISA Kit for Stanniocalcin 1 (STC1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"A novel human cDNA highly homologous to the fish hormone stanniocalcin."
Mol. Cell. Endocrinol. 112:241-247(1995) [PubMed] [Europe PMC] [Abstract]
"Human stanniocalcin: a possible hormonal regulator of mineral metabolism."
Proc. Natl. Acad. Sci. U.S.A. 93:1792-1796(1996) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"DNA sequence and analysis of human chromosome 8."
Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Comparative analysis of mammalian stanniocalcin genes."
Endocrinology 139:4714-4725(1998) [PubMed] [Europe PMC] [Abstract]
"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]