Synapsin I (SYN1)
SYN1a; SYN1b; SYNI; Brain protein 4.1
The synapsin I protein is a member of the synapsin family that are neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases.The phosphoprotein plays a role in regulation of axonogenesis and synaptogenesis.
The protein serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal.Synapsin I is found in two isoforms of the protein, Synapsin Ia and Synapsin Ib, with Synapsin Ib being a slightly shorter version of the protein.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT974Hu01 | Recombinant Synapsin I (SYN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT974Hu01 | Monoclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IP. |
| PAT974Hu01 | Polyclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT974Hu01 | CLIA Kit for Synapsin I (SYN1) | CLIA assay for Antigen Detection |
| ELT974Hu01 | ELISA Kit for Synapsin I (SYN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT974Mu01 | Recombinant Synapsin I (SYN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT974Mu01 | Monoclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IP. |
| PAT974Mu01 | Polyclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT974Mu01 | CLIA Kit for Synapsin I (SYN1) | CLIA assay for Antigen Detection |
| ELT974Mu01 | ELISA Kit for Synapsin I (SYN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT974Ra01 | Recombinant Synapsin I (SYN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT974Ra01 | Monoclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IP. |
| PAT974Ra01 | Polyclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT974Ra01 | CLIA Kit for Synapsin I (SYN1) | CLIA assay for Antigen Detection |
| ELT974Ra01 | ELISA Kit for Synapsin I (SYN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT974Ca01 | Recombinant Synapsin I (SYN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT974Ca01 | Monoclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IP. |
| PAT974Ca01 | Polyclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT974Ca01 | CLIA Kit for Synapsin I (SYN1) | CLIA assay for Antigen Detection |
| ELT974Ca01 | ELISA Kit for Synapsin I (SYN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT974Po01 | Recombinant Synapsin I (SYN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT974Po01 | Monoclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IP. |
| PAT974Po01 | Polyclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT974Po01 | CLIA Kit for Synapsin I (SYN1) | CLIA assay for Antigen Detection |
| ELT974Po01 | ELISA Kit for Synapsin I (SYN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT974Bo01 | Recombinant Synapsin I (SYN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT974Bo01 | Monoclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IP. |
| PAT974Bo01 | Polyclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT974Bo01 | CLIA Kit for Synapsin I (SYN1) | CLIA assay for Antigen Detection |
| ELT974Bo01 | ELISA Kit for Synapsin I (SYN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT974Rb01 | Recombinant Synapsin I (SYN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT974Rb01 | Monoclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IP. |
| PAT974Rb01 | Polyclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT974Rb01 | CLIA Kit for Synapsin I (SYN1) | CLIA assay for Antigen Detection |
| ELT974Rb01 | ELISA Kit for Synapsin I (SYN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT974Mo01 | Recombinant Synapsin I (SYN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT974Mo01 | Monoclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IP. |
| PAT974Mo01 | Polyclonal Antibody to Synapsin I (SYN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT974Mo01 | CLIA Kit for Synapsin I (SYN1) | CLIA assay for Antigen Detection |
| ELT974Mo01 | ELISA Kit for Synapsin I (SYN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"The structure of the human synapsin I gene and protein."
J. Biol. Chem. 265:7849-7852(1990) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of the human X chromosome."
Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
"The 5'-flanking region of the synapsin I gene. A G+C-rich, TATA- and CAAT-less, phylogenetically conserved sequence with cell type-specific promoter function."
J. Biol. Chem. 265:14932-14937(1990) [PubMed] [Europe PMC] [Abstract]
"Identification of a mutation in synapsin I, a synaptic vesicle protein, in a family with epilepsy."
J. Med. Genet. 41:183-187(2004) [PubMed] [Europe PMC] [Abstract]
"Phosphoproteomic analysis of synaptosomes from human cerebral cortex."
J. Proteome Res. 4:306-315(2005) [PubMed] [Europe PMC] [Abstract]
"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]