Galectin 8 (GAL8)
LGALS8; PCTA1; Po66-CBP; Prostate Carcinoma Tumor Antigen 1; Lectin,Galactoside-Binding Soluble 8; Po66 carbohydrate-binding protein; Prostate carcinoma tumor antigen 1
Galectin-8 is one of the galectins, beta-galactoside-binding lectins with conserved carbohydrate recognition domains (CRD). Galectin-8 essentially consists of two carbohydrate recognition domains separated by a linker that bears no similarity to any known protein. The gene symbol is LGALS8 [galactose-specific soluble lectin 8; lectin galactoside-binding soluble 8]. Galectin-8 has been identified originally as PCTA1 [Prostate carcinoma tumor antigen 1], an antigen expressed by prostate cancer cells .
Several isoforms appear to be expressed differentially in various tumoral cells . The protein is identical with Po66-CBP [Po66 carbohydrate-binding protein], identified by the Po66 monoclonal antibody.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT821Hu01 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT821Hu01 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. |
| PAT821Hu01 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT821Hu01 | CLIA Kit for Galectin 8 (GAL8) | CLIA assay for Antigen Detection |
| ELT821Hu01 | ELISA Kit for Galectin 8 (GAL8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT821Mu01 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT821Mu01 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. |
| PAT821Mu01 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT821Mu01 | CLIA Kit for Galectin 8 (GAL8) | CLIA assay for Antigen Detection |
| ELT821Mu01 | ELISA Kit for Galectin 8 (GAL8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT821Ra01 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT821Ra01 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. |
| PAT821Ra01 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT821Ra01 | CLIA Kit for Galectin 8 (GAL8) | CLIA assay for Antigen Detection |
| ELT821Ra01 | ELISA Kit for Galectin 8 (GAL8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT821Ca01 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT821Ca01 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. |
| PAT821Ca01 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT821Ca01 | CLIA Kit for Galectin 8 (GAL8) | CLIA assay for Antigen Detection |
| ELT821Ca01 | ELISA Kit for Galectin 8 (GAL8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT821Po01 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT821Po01 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. |
| PAT821Po01 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT821Po01 | CLIA Kit for Galectin 8 (GAL8) | CLIA assay for Antigen Detection |
| ELT821Po01 | ELISA Kit for Galectin 8 (GAL8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT821Bo01 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT821Bo01 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. |
| PAT821Bo01 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT821Bo01 | CLIA Kit for Galectin 8 (GAL8) | CLIA assay for Antigen Detection |
| ELT821Bo01 | ELISA Kit for Galectin 8 (GAL8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT821Rb01 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT821Rb01 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. |
| PAT821Rb01 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT821Rb01 | CLIA Kit for Galectin 8 (GAL8) | CLIA assay for Antigen Detection |
| ELT821Rb01 | ELISA Kit for Galectin 8 (GAL8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT821Mo01 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT821Mo01 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. |
| PAT821Mo01 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT821Mo01 | CLIA Kit for Galectin 8 (GAL8) | CLIA assay for Antigen Detection |
| ELT821Mo01 | ELISA Kit for Galectin 8 (GAL8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family."
Proc. Natl. Acad. Sci. U.S.A. 93:7252-7257(1996) [PubMed] [Europe PMC] [Abstract]
"Galectin-8: on the road from structure to function."
Trends Glycosci. Glycotechnol. 9:103-112(1997)
"Molecular characterization of prostate carcinoma tumor antigen-1, PCTA-1, a human galectin-8 related gene."
Oncogene 19:4405-4416(2000) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Solution structure of the C-terminal Gal-bind lectin protein from human galectin-8."
Submitted (FEB-2008) to the PDB data bank
"Crystal structure of N-terminal domain of human galectin-8."
Submitted (MAY-2008) to the PDB data bank
"Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans."
J. Biol. Chem. 286:11346-11355(2011) [PubMed] [Europe PMC] [Abstract]