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Asparaginyl tRNA Synthetase (NARS)

AsnRS; NARS1; KS; Asparagine tRNA Ligase 1,Cytoplasmic

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Asparaginyl-tRNA synthetase is localized to the cytoplasm and belongs to the class II family of tRNA synthetases. The N-terminal domain represents the signature sequence for the eukaryotic asparaginyl-tRNA synthetases.
Hybrids selected at 39 degrees C required the presence of human chromosome 18. Temperature-resistant hybrid cells contained 2 forms of ASNRS: 1 highly thermal resistant, like the human enzyme, and 1 highly thermolabile, like the CHO mutant enzyme. The deduced 548-amino acid protein has a predicted molecular mass of 62.9 kD and shares 53% sequence identity with the S. cerevisiae homolog.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT788Hu01 Recombinant Asparaginyl tRNA Synthetase (NARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT788Hu01 Monoclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IP.
PAT788Hu01 Polyclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IF.
Assay Kits CLT788Hu01 CLIA Kit for Asparaginyl tRNA Synthetase (NARS) CLIA assay for Antigen Detection
ELT788Hu01 ELISA Kit for Asparaginyl tRNA Synthetase (NARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT788Mu01 Recombinant Asparaginyl tRNA Synthetase (NARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT788Mu01 Monoclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IP.
PAT788Mu01 Polyclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IF.
Assay Kits CLT788Mu01 CLIA Kit for Asparaginyl tRNA Synthetase (NARS) CLIA assay for Antigen Detection
ELT788Mu01 ELISA Kit for Asparaginyl tRNA Synthetase (NARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT788Ra01 Recombinant Asparaginyl tRNA Synthetase (NARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT788Ra01 Monoclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IP.
PAT788Ra01 Polyclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IF.
Assay Kits CLT788Ra01 CLIA Kit for Asparaginyl tRNA Synthetase (NARS) CLIA assay for Antigen Detection
ELT788Ra01 ELISA Kit for Asparaginyl tRNA Synthetase (NARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT788Ca01 Recombinant Asparaginyl tRNA Synthetase (NARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT788Ca01 Monoclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IP.
PAT788Ca01 Polyclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IF.
Assay Kits CLT788Ca01 CLIA Kit for Asparaginyl tRNA Synthetase (NARS) CLIA assay for Antigen Detection
ELT788Ca01 ELISA Kit for Asparaginyl tRNA Synthetase (NARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT788Po01 Recombinant Asparaginyl tRNA Synthetase (NARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT788Po01 Monoclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IP.
PAT788Po01 Polyclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IF.
Assay Kits CLT788Po01 CLIA Kit for Asparaginyl tRNA Synthetase (NARS) CLIA assay for Antigen Detection
ELT788Po01 ELISA Kit for Asparaginyl tRNA Synthetase (NARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT788Bo01 Recombinant Asparaginyl tRNA Synthetase (NARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT788Bo01 Monoclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IP.
PAT788Bo01 Polyclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IF.
Assay Kits CLT788Bo01 CLIA Kit for Asparaginyl tRNA Synthetase (NARS) CLIA assay for Antigen Detection
ELT788Bo01 ELISA Kit for Asparaginyl tRNA Synthetase (NARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT788Rb01 Recombinant Asparaginyl tRNA Synthetase (NARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT788Rb01 Monoclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IP.
PAT788Rb01 Polyclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IF.
Assay Kits CLT788Rb01 CLIA Kit for Asparaginyl tRNA Synthetase (NARS) CLIA assay for Antigen Detection
ELT788Rb01 ELISA Kit for Asparaginyl tRNA Synthetase (NARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT788Mo01 Recombinant Asparaginyl tRNA Synthetase (NARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT788Mo01 Monoclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IP.
PAT788Mo01 Polyclonal Antibody to Asparaginyl tRNA Synthetase (NARS) WB; IHC; ICC; IF.
Assay Kits CLT788Mo01 CLIA Kit for Asparaginyl tRNA Synthetase (NARS) CLIA assay for Antigen Detection
ELT788Mo01 ELISA Kit for Asparaginyl tRNA Synthetase (NARS) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Human cytosolic asparaginyl-tRNA synthetase: cDNA sequence, functional expression in Escherichia coli and characterization as human autoantigen."
Nucleic Acids Res. 26:521-524(1998) [PubMed] [Europe PMC] [Abstract]

"Human asparaginyl-tRNA synthetase: molecular cloning and the inference of the evolutionary history of Asx-tRNA synthetase family."
Nucleic Acids Res. 26:5045-5051(1998) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 18."
Nature 437:551-555(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini."
Proc. Natl. Acad. Sci. U.S.A. 106:19310-19315(2009) [PubMed] [Europe PMC] [Abstract]

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"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]