Call Now

Glutaminyl tRNA Synthetase (QARS)

GLNRS; Glutamine tRNA Ligase

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT782Hu01 Recombinant Glutaminyl tRNA Synthetase (QARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT782Hu01 Monoclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IP.
PAT782Hu01 Polyclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IF.
Assay Kits CLT782Hu01 CLIA Kit for Glutaminyl tRNA Synthetase (QARS) CLIA assay for Antigen Detection
ELT782Hu01 ELISA Kit for Glutaminyl tRNA Synthetase (QARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT782Mu01 Recombinant Glutaminyl tRNA Synthetase (QARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT782Mu01 Monoclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IP.
PAT782Mu01 Polyclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IF.
Assay Kits CLT782Mu01 CLIA Kit for Glutaminyl tRNA Synthetase (QARS) CLIA assay for Antigen Detection
ELT782Mu01 ELISA Kit for Glutaminyl tRNA Synthetase (QARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT782Ra01 Recombinant Glutaminyl tRNA Synthetase (QARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT782Ra01 Monoclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IP.
PAT782Ra01 Polyclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IF.
Assay Kits CLT782Ra01 CLIA Kit for Glutaminyl tRNA Synthetase (QARS) CLIA assay for Antigen Detection
ELT782Ra01 ELISA Kit for Glutaminyl tRNA Synthetase (QARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT782Ca01 Recombinant Glutaminyl tRNA Synthetase (QARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT782Ca01 Monoclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IP.
PAT782Ca01 Polyclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IF.
Assay Kits CLT782Ca01 CLIA Kit for Glutaminyl tRNA Synthetase (QARS) CLIA assay for Antigen Detection
ELT782Ca01 ELISA Kit for Glutaminyl tRNA Synthetase (QARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT782Po01 Recombinant Glutaminyl tRNA Synthetase (QARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT782Po01 Monoclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IP.
PAT782Po01 Polyclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IF.
Assay Kits CLT782Po01 CLIA Kit for Glutaminyl tRNA Synthetase (QARS) CLIA assay for Antigen Detection
ELT782Po01 ELISA Kit for Glutaminyl tRNA Synthetase (QARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT782Bo01 Recombinant Glutaminyl tRNA Synthetase (QARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT782Bo01 Monoclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IP.
PAT782Bo01 Polyclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IF.
Assay Kits CLT782Bo01 CLIA Kit for Glutaminyl tRNA Synthetase (QARS) CLIA assay for Antigen Detection
ELT782Bo01 ELISA Kit for Glutaminyl tRNA Synthetase (QARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT782Rb01 Recombinant Glutaminyl tRNA Synthetase (QARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT782Rb01 Monoclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IP.
PAT782Rb01 Polyclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IF.
Assay Kits CLT782Rb01 CLIA Kit for Glutaminyl tRNA Synthetase (QARS) CLIA assay for Antigen Detection
ELT782Rb01 ELISA Kit for Glutaminyl tRNA Synthetase (QARS) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT782Mo01 Recombinant Glutaminyl tRNA Synthetase (QARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT782Mo01 Monoclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IP.
PAT782Mo01 Polyclonal Antibody to Glutaminyl tRNA Synthetase (QARS) WB; IHC; ICC; IF.
Assay Kits CLT782Mo01 CLIA Kit for Glutaminyl tRNA Synthetase (QARS) CLIA assay for Antigen Detection
ELT782Mo01 ELISA Kit for Glutaminyl tRNA Synthetase (QARS) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme as a case of horizontal gene transfer."
Proc. Natl. Acad. Sci. U.S.A. 91:8670-8674(1994) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence, annotation and analysis of human chromosome 3."
Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

, Submitted (JUL-2007) to UniProtKB

"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

"Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures."
Am. J. Hum. Genet. 94:547-558(2014) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]