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Kallikrein 2 (KLK2)

KLK2A2; HK2; Prostatic Kallikrein-Related Peptidase 2; Glandular kallikrein-1; Tissue kallikrein-2

Kallikrein-2 is a protein encoded by the KLK2 gene.The glandular kallikreins are a distinct group of serine proteases with molecular masses of 25,000 to 40,000 and an ability to release vasoactive peptides from kininogen in vitro, although the kininogenase activity of different kallikreins is highly variable. The true physiologic role of specific kallikreins is often unrelated to the kininogenase activity. In the mouse a major site of kallikrein synthesis is the male submaxillary gland. Glandular kallikreins are also synthesized in the pancreas and kidney. The several kallikreins found in this tissue include epidermal growth factor-binding protein (EGF-BP) and the gamma subunit of nerve growth factor (NGFG;), which are responsible for the processing of EGF and NGF , respectively.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT678Hu01 Recombinant Kallikrein 2 (KLK2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT678Hu01 Monoclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IP.
PAT678Hu01 Polyclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IF.
Assay Kits CLT678Hu01 CLIA Kit for Kallikrein 2 (KLK2) CLIA assay for Antigen Detection
ELT678Hu01 ELISA Kit for Kallikrein 2 (KLK2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT678Mu01 Recombinant Kallikrein 2 (KLK2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT678Mu01 Monoclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IP.
PAT678Mu01 Polyclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IF.
Assay Kits CLT678Mu01 CLIA Kit for Kallikrein 2 (KLK2) CLIA assay for Antigen Detection
ELT678Mu01 ELISA Kit for Kallikrein 2 (KLK2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT678Ra01 Recombinant Kallikrein 2 (KLK2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT678Ra01 Monoclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IP.
PAT678Ra01 Polyclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IF.
Assay Kits CLT678Ra01 CLIA Kit for Kallikrein 2 (KLK2) CLIA assay for Antigen Detection
ELT678Ra01 ELISA Kit for Kallikrein 2 (KLK2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT678Ca01 Recombinant Kallikrein 2 (KLK2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT678Ca01 Monoclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IP.
PAT678Ca01 Polyclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IF.
Assay Kits CLT678Ca01 CLIA Kit for Kallikrein 2 (KLK2) CLIA assay for Antigen Detection
ELT678Ca01 ELISA Kit for Kallikrein 2 (KLK2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT678Po01 Recombinant Kallikrein 2 (KLK2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT678Po01 Monoclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IP.
PAT678Po01 Polyclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IF.
Assay Kits CLT678Po01 CLIA Kit for Kallikrein 2 (KLK2) CLIA assay for Antigen Detection
ELT678Po01 ELISA Kit for Kallikrein 2 (KLK2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT678Bo01 Recombinant Kallikrein 2 (KLK2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT678Bo01 Monoclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IP.
PAT678Bo01 Polyclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IF.
Assay Kits CLT678Bo01 CLIA Kit for Kallikrein 2 (KLK2) CLIA assay for Antigen Detection
ELT678Bo01 ELISA Kit for Kallikrein 2 (KLK2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT678Rb01 Recombinant Kallikrein 2 (KLK2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT678Rb01 Monoclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IP.
PAT678Rb01 Polyclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IF.
Assay Kits CLT678Rb01 CLIA Kit for Kallikrein 2 (KLK2) CLIA assay for Antigen Detection
ELT678Rb01 ELISA Kit for Kallikrein 2 (KLK2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT678Mo01 Recombinant Kallikrein 2 (KLK2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT678Mo01 Monoclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IP.
PAT678Mo01 Polyclonal Antibody to Kallikrein 2 (KLK2) WB; IHC; ICC; IF.
Assay Kits CLT678Mo01 CLIA Kit for Kallikrein 2 (KLK2) CLIA assay for Antigen Detection
ELT678Mo01 ELISA Kit for Kallikrein 2 (KLK2) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Primary structure of a human glandular kallikrein gene."
DNA 6:429-437(1987) [PubMed] [Europe PMC] [Abstract]

"Identification and androgen-regulated expression of two major human glandular kallikrein-1 (hGK-1) mRNA species."
Mol. Cell. Endocrinol. 76:181-190(1991) [PubMed] [Europe PMC] [Abstract]

"Identification of three new alternate human kallikrein 2 transcripts: evidence of long transcript and alternative splicing."
Biochem. Biophys. Res. Commun. 264:833-839(1999) [PubMed] [Europe PMC] [Abstract]

"Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region."
Gene 257:119-130(2000) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biology of human chromosome 19."
Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"An unappreciated role for RNA surveillance."
Genome Biol. 5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]

"Characterization of single-nucleotide polymorphisms in coding regions of human genes."
Nat. Genet. 22:231-238(1999) [PubMed] [Europe PMC] [Abstract]

Erratum
Nat. Genet. 23:373-373(1999)