Fasciculation And Elongation Protein Zeta 2 (FEz2)
FE-z2; HUM3CL; Zygin II
Fasciculation and elongation protein zeta-2 is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin.The C. elegans gene unc-76 ('unc' for 'uncoordinated') is necessary for normal axonal bundling and elongation within axon bundles. By searching an EST database with the UNC-76 sequence, Bloom and Horvitz identified 2 human genes with sequence similarity to unc-76; they named these novel genes FEZ1 and FEZ2. The longest FEZ2 EST identified encodes a deduced 251-amino acid partial protein lacking N-terminal sequence. FEZ2 shares 49% and 34% amino acid sequence identity with FEZ1 and UNC-76, respectively, in the regions of overlap.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT626Hu01 | Recombinant Fasciculation And Elongation Protein Zeta 2 (FEz2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT626Hu01 | Monoclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IP. |
| PAT626Hu01 | Polyclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT626Hu01 | CLIA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | CLIA assay for Antigen Detection |
| ELT626Hu01 | ELISA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT626Mu01 | Recombinant Fasciculation And Elongation Protein Zeta 2 (FEz2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT626Mu01 | Monoclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IP. |
| PAT626Mu01 | Polyclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT626Mu01 | CLIA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | CLIA assay for Antigen Detection |
| ELT626Mu01 | ELISA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT626Ra01 | Recombinant Fasciculation And Elongation Protein Zeta 2 (FEz2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT626Ra01 | Monoclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IP. |
| PAT626Ra01 | Polyclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT626Ra01 | CLIA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | CLIA assay for Antigen Detection |
| ELT626Ra01 | ELISA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT626Ca01 | Recombinant Fasciculation And Elongation Protein Zeta 2 (FEz2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT626Ca01 | Monoclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IP. |
| PAT626Ca01 | Polyclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT626Ca01 | CLIA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | CLIA assay for Antigen Detection |
| ELT626Ca01 | ELISA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT626Po01 | Recombinant Fasciculation And Elongation Protein Zeta 2 (FEz2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT626Po01 | Monoclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IP. |
| PAT626Po01 | Polyclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT626Po01 | CLIA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | CLIA assay for Antigen Detection |
| ELT626Po01 | ELISA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT626Bo01 | Recombinant Fasciculation And Elongation Protein Zeta 2 (FEz2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT626Bo01 | Monoclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IP. |
| PAT626Bo01 | Polyclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT626Bo01 | CLIA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | CLIA assay for Antigen Detection |
| ELT626Bo01 | ELISA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT626Rb01 | Recombinant Fasciculation And Elongation Protein Zeta 2 (FEz2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT626Rb01 | Monoclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IP. |
| PAT626Rb01 | Polyclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT626Rb01 | CLIA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | CLIA assay for Antigen Detection |
| ELT626Rb01 | ELISA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT626Mo01 | Recombinant Fasciculation And Elongation Protein Zeta 2 (FEz2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT626Mo01 | Monoclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IP. |
| PAT626Mo01 | Polyclonal Antibody to Fasciculation And Elongation Protein Zeta 2 (FEz2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT626Mo01 | CLIA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | CLIA assay for Antigen Detection |
| ELT626Mo01 | ELISA Kit for Fasciculation And Elongation Protein Zeta 2 (FEz2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Identification of a tissue-non-specific homologue of axonal fasciculation and elongation protein zeta-1."
Biochem. Biophys. Res. Commun. 313:738-744(2004) [PubMed] [Europe PMC] [Abstract]
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning."
Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000) [PubMed] [Europe PMC] [Abstract]
"The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation."
Proc. Natl. Acad. Sci. U.S.A. 94:3414-3419(1997) [PubMed] [Europe PMC] [Abstract]
"FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region."
J. Biol. Chem. 281:9869-9881(2006) [PubMed] [Europe PMC] [Abstract]
"Human FEZ1 protein forms a disulfide bond mediated dimer: implications for cargo transport."
J. Proteome Res. 9:4595-4603(2010) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]