S100 Calcium Binding Protein A14 (S100A14)
S100-A14; S100-A15; S100A15; BCMP84; S114
S100A14 is a member of a subfamily of proteins related by Ca(2+)-binding motifs to the EF-hand Ca(2+)-binding protein superfamily.Using a proteomics approach to identify genes upregulated in breast cancer, followed by database analysis and PCR of a breast carcinoma cell line, Adam et al. (2003) cloned S100A14, which they called BCMP84. BCMP84 expression in normal tissue was restricted to stratified squamous epithelium of skin, cervix, and tonsil. Weak staining was seen in normal breast ductal tissue, but strong immunoreactivity was detected in 10 of 58 (17%) breast cancer tissues. BCMP84 was expressed in the plasma membrane of transiently transfected breast carcinoma cells.By fluorescence in situ hybridization, Pietas et al. (2002) mapped the S100A14 gene to chromosome 1q21 in a cluster with at least 15 other S100 genes.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT624Hu01 | Recombinant S100 Calcium Binding Protein A14 (S100A14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT624Hu01 | Monoclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IP. |
| PAT624Hu01 | Polyclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT624Hu01 | CLIA Kit for S100 Calcium Binding Protein A14 (S100A14) | CLIA assay for Antigen Detection |
| ELT624Hu01 | ELISA Kit for S100 Calcium Binding Protein A14 (S100A14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT624Mu01 | Recombinant S100 Calcium Binding Protein A14 (S100A14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT624Mu01 | Monoclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IP. |
| PAT624Mu01 | Polyclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT624Mu01 | CLIA Kit for S100 Calcium Binding Protein A14 (S100A14) | CLIA assay for Antigen Detection |
| ELT624Mu01 | ELISA Kit for S100 Calcium Binding Protein A14 (S100A14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT624Ra01 | Recombinant S100 Calcium Binding Protein A14 (S100A14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT624Ra01 | Monoclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IP. |
| PAT624Ra01 | Polyclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT624Ra01 | CLIA Kit for S100 Calcium Binding Protein A14 (S100A14) | CLIA assay for Antigen Detection |
| ELT624Ra01 | ELISA Kit for S100 Calcium Binding Protein A14 (S100A14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT624Ca01 | Recombinant S100 Calcium Binding Protein A14 (S100A14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT624Ca01 | Monoclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IP. |
| PAT624Ca01 | Polyclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT624Ca01 | CLIA Kit for S100 Calcium Binding Protein A14 (S100A14) | CLIA assay for Antigen Detection |
| ELT624Ca01 | ELISA Kit for S100 Calcium Binding Protein A14 (S100A14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT624Po01 | Recombinant S100 Calcium Binding Protein A14 (S100A14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT624Po01 | Monoclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IP. |
| PAT624Po01 | Polyclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT624Po01 | CLIA Kit for S100 Calcium Binding Protein A14 (S100A14) | CLIA assay for Antigen Detection |
| ELT624Po01 | ELISA Kit for S100 Calcium Binding Protein A14 (S100A14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT624Bo01 | Recombinant S100 Calcium Binding Protein A14 (S100A14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT624Bo01 | Monoclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IP. |
| PAT624Bo01 | Polyclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT624Bo01 | CLIA Kit for S100 Calcium Binding Protein A14 (S100A14) | CLIA assay for Antigen Detection |
| ELT624Bo01 | ELISA Kit for S100 Calcium Binding Protein A14 (S100A14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT624Rb01 | Recombinant S100 Calcium Binding Protein A14 (S100A14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT624Rb01 | Monoclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IP. |
| PAT624Rb01 | Polyclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT624Rb01 | CLIA Kit for S100 Calcium Binding Protein A14 (S100A14) | CLIA assay for Antigen Detection |
| ELT624Rb01 | ELISA Kit for S100 Calcium Binding Protein A14 (S100A14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT624Mo01 | Recombinant S100 Calcium Binding Protein A14 (S100A14) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT624Mo01 | Monoclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IP. |
| PAT624Mo01 | Polyclonal Antibody to S100 Calcium Binding Protein A14 (S100A14) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT624Mo01 | CLIA Kit for S100 Calcium Binding Protein A14 (S100A14) | CLIA assay for Antigen Detection |
| ELT624Mo01 | ELISA Kit for S100 Calcium Binding Protein A14 (S100A14) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Molecular cloning and characterization of the human S100A14 gene encoding a novel member of the S100 family."
Genomics 79:513-522(2002) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"S100A14 stimulates cell proliferation and induces cell apoptosis at different concentrations via receptor for advanced glycation end products (RAGE)."
PLoS ONE 6:E19375-E19375(2011) [PubMed] [Europe PMC] [Abstract]
"Involvement of S100A14 protein in cell invasion by affecting expression and function of matrix metalloproteinase (MMP)-2 via p53-dependent transcriptional regulation."
J. Biol. Chem. 287:17109-17119(2012) [PubMed] [Europe PMC] [Abstract]
"S100A14 inhibits proliferation of oral carcinoma derived cells through G1-arrest."
Oral Oncol. 48:219-225(2012) [PubMed] [Europe PMC] [Abstract]
"Solution structure and dynamics of human S100A14."
J. Biol. Inorg. Chem. 18:183-194(2013) [PubMed] [Europe PMC] [Abstract]