Thyroid Stimulating Hormone Beta (TSHb)
TSH-B; Thyrotropin beta chain; Thyrotropin alfa
Thyrotropin-stimulating hormone (TSH) is a noncovalently linked glycoprotein heterodimer and is part of a family of pituitary hormones containing a common alpha subunit (TSHA) and a unique beta subunit that confers specificity.Using bovine TSHB cDNA as probe, Hayashizaki et al. (1985) cloned TSHB from human liver and leukocyte genomic DNA libraries. Human TSHB encodes a deduced protein consisting of a 20-amino acid signal sequence, a mature protein of 112 amino acids, and a C-terminal extension of 6 hydrophobic amino acids. Wondisford et al. (1988) also cloned the human TSHB gene.Wondisford et al. (1988) determined that the TSHB gene contains 3 exons, the first of which is noncoding. The rat TSHB gene also contains one 5-prime noncoding exon, whereas the mouse Tshb gene contains 3.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT568Hu01 | Recombinant Thyroid Stimulating Hormone Beta (TSHb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT568Hu01 | Monoclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IP. |
| PAT568Hu01 | Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT568Hu01 | CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) | CLIA assay for Antigen Detection |
| ELT568Hu01 | ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT568Mu01 | Recombinant Thyroid Stimulating Hormone Beta (TSHb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT568Mu01 | Monoclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IP. |
| PAT568Mu01 | Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT568Mu01 | CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) | CLIA assay for Antigen Detection |
| ELT568Mu01 | ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT568Ra01 | Recombinant Thyroid Stimulating Hormone Beta (TSHb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT568Ra01 | Monoclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IP. |
| PAT568Ra01 | Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT568Ra01 | CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) | CLIA assay for Antigen Detection |
| ELT568Ra01 | ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT568Ca01 | Recombinant Thyroid Stimulating Hormone Beta (TSHb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT568Ca01 | Monoclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IP. |
| PAT568Ca01 | Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT568Ca01 | CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) | CLIA assay for Antigen Detection |
| ELT568Ca01 | ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT568Po01 | Recombinant Thyroid Stimulating Hormone Beta (TSHb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT568Po01 | Monoclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IP. |
| PAT568Po01 | Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT568Po01 | CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) | CLIA assay for Antigen Detection |
| ELT568Po01 | ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT568Bo01 | Recombinant Thyroid Stimulating Hormone Beta (TSHb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT568Bo01 | Monoclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IP. |
| PAT568Bo01 | Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT568Bo01 | CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) | CLIA assay for Antigen Detection |
| ELT568Bo01 | ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT568Rb01 | Recombinant Thyroid Stimulating Hormone Beta (TSHb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT568Rb01 | Monoclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IP. |
| PAT568Rb01 | Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT568Rb01 | CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) | CLIA assay for Antigen Detection |
| ELT568Rb01 | ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT568Mo01 | Recombinant Thyroid Stimulating Hormone Beta (TSHb) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT568Mo01 | Monoclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IP. |
| PAT568Mo01 | Polyclonal Antibody to Thyroid Stimulating Hormone Beta (TSHb) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT568Mo01 | CLIA Kit for Thyroid Stimulating Hormone Beta (TSHb) | CLIA assay for Antigen Detection |
| ELT568Mo01 | ELISA Kit for Thyroid Stimulating Hormone Beta (TSHb) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Molecular cloning of the human thyrotropin-beta subunit gene."
FEBS Lett. 188:394-400(1985) [PubMed] [Europe PMC] [Abstract]
"The human thyrotropin beta-subunit gene differs in 5' structure from murine TSH-beta genes."
DNA 7:691-699(1988) [PubMed] [Europe PMC] [Abstract]
"The structure of the human thyrotropin beta-subunit gene."
Gene 73:489-497(1988) [PubMed] [Europe PMC] [Abstract]
"Isolation and characterization of the human thyrotropin beta-subunit gene. Differences in gene structure and promoter function from murine species."
J. Biol. Chem. 263:12538-12542(1988) [PubMed] [Europe PMC] [Abstract]
"Structure and regulation of human thyroid-stimulating hormone (TSH) gene."
Nippon Rinsho 52:940-947(1994) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"A novel thyroid stimulating hormone beta-subunit isoform in human pituitary, peripheral blood leukocytes, and thyroid."
Gen. Comp. Endocrinol. 162:241-244(2009) [PubMed] [Europe PMC] [Abstract]
"Human pituitary thyrotropin. The primary structure of the alpha and beta subunits."
Can. J. Biochem. 55:755-760(1977) [PubMed] [Europe PMC] [Abstract]