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Troponin C Type 2, Fast (TNNC2)

Troponin C, skeletal muscle

The troponin C protein is the calcium-binding subunit of the troponin complex. It occurs in 2 distinct isoforms: fast skeletal troponin C, which is expressed exclusively in fast-twitch skeletal muscle, and slow/cardiac troponin C, which is expressed in both cardiac and slow-twitch skeletal muscle. Gahlmann and Kedes (1990) described the structure and sequence of the gene for fast-twitch troponin C.
By PCR-based analysis of a monochromosomal hybrid panel followed by analysis of the Genebridge 4 radiation hybrid panel, Townsend et al. (1997) mapped the TNNC2 gene to chromosome 20. Tiso et al. (1997) independently mapped the TNNC2 gene to 20q12-q13.11 using PCR of radiation hybrids.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT553Hu01 Recombinant Troponin C Type 2, Fast (TNNC2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT553Hu01 Monoclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IP.
PAT553Hu01 Polyclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IF.
Assay Kits CLT553Hu01 CLIA Kit for Troponin C Type 2, Fast (TNNC2) CLIA assay for Antigen Detection
ELT553Hu01 ELISA Kit for Troponin C Type 2, Fast (TNNC2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT553Mu01 Recombinant Troponin C Type 2, Fast (TNNC2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT553Mu01 Monoclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IP.
PAT553Mu01 Polyclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IF.
Assay Kits CLT553Mu01 CLIA Kit for Troponin C Type 2, Fast (TNNC2) CLIA assay for Antigen Detection
ELT553Mu01 ELISA Kit for Troponin C Type 2, Fast (TNNC2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT553Ra01 Recombinant Troponin C Type 2, Fast (TNNC2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT553Ra01 Monoclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IP.
PAT553Ra01 Polyclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IF.
Assay Kits CLT553Ra01 CLIA Kit for Troponin C Type 2, Fast (TNNC2) CLIA assay for Antigen Detection
ELT553Ra01 ELISA Kit for Troponin C Type 2, Fast (TNNC2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT553Ca01 Recombinant Troponin C Type 2, Fast (TNNC2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT553Ca01 Monoclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IP.
PAT553Ca01 Polyclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IF.
Assay Kits CLT553Ca01 CLIA Kit for Troponin C Type 2, Fast (TNNC2) CLIA assay for Antigen Detection
ELT553Ca01 ELISA Kit for Troponin C Type 2, Fast (TNNC2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT553Po01 Recombinant Troponin C Type 2, Fast (TNNC2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT553Po01 Monoclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IP.
PAT553Po01 Polyclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IF.
Assay Kits CLT553Po01 CLIA Kit for Troponin C Type 2, Fast (TNNC2) CLIA assay for Antigen Detection
ELT553Po01 ELISA Kit for Troponin C Type 2, Fast (TNNC2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT553Bo01 Recombinant Troponin C Type 2, Fast (TNNC2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT553Bo01 Monoclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IP.
PAT553Bo01 Polyclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IF.
Assay Kits CLT553Bo01 CLIA Kit for Troponin C Type 2, Fast (TNNC2) CLIA assay for Antigen Detection
ELT553Bo01 ELISA Kit for Troponin C Type 2, Fast (TNNC2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT553Rb01 Recombinant Troponin C Type 2, Fast (TNNC2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT553Rb01 Monoclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IP.
PAT553Rb01 Polyclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IF.
Assay Kits CLT553Rb01 CLIA Kit for Troponin C Type 2, Fast (TNNC2) CLIA assay for Antigen Detection
ELT553Rb01 ELISA Kit for Troponin C Type 2, Fast (TNNC2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT553Mo01 Recombinant Troponin C Type 2, Fast (TNNC2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT553Mo01 Monoclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IP.
PAT553Mo01 Polyclonal Antibody to Troponin C Type 2, Fast (TNNC2) WB; IHC; ICC; IF.
Assay Kits CLT553Mo01 CLIA Kit for Troponin C Type 2, Fast (TNNC2) CLIA assay for Antigen Detection
ELT553Mo01 ELISA Kit for Troponin C Type 2, Fast (TNNC2) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Differential expression of slow and fast skeletal muscle troponin C. Slow skeletal muscle troponin C is expressed in human fibroblasts."
J. Mol. Biol. 201:379-391(1988) [PubMed] [Europe PMC] [Abstract]

"Cloning, structural analysis, and expression of the human fast twitch skeletal muscle troponin C gene."
J. Biol. Chem. 265:12520-12528(1990) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 20."
Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Human skeletal muscle proteins. The primary structure of troponin C."
J. Mol. Evol. 8:251-270(1976) [PubMed] [Europe PMC] [Abstract]