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Cytochrome C Oxidase Subunit III (COX3)

MTCO3; MT-CO3; COIII; COXIII; Mitochondrially Encoded Cytochrome C Oxidase III

Cytochrome c oxidase subunit III is one of main transmembrane subunits of cytochrome c oxidase. Cytochrome c oxidase is an oligomeric enzymatic complex that is located in the mitochondrial inner membrane of eukaryotes and in the plasma membrane of aerobic prokaryotes. The core structure of prokaryotic and eukaryotic cytochrome c oxidase contains three common subunits, I, II and III. In prokaryotes, subunits I and III can be fused and a fourth subunit is sometimes found, whereas in eukaryotes there are a variable number of additional small subunits.
As the bacterial respiratory systems are branched, they have a number of distinct terminal oxidases, rather than the single cytochrome c oxidase present in the eukaryotic mitochondrial systems.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT496Hu01 Recombinant Cytochrome C Oxidase Subunit III (COX3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT496Hu01 Monoclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IP.
PAT496Hu01 Polyclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IF.
Assay Kits CLT496Hu01 CLIA Kit for Cytochrome C Oxidase Subunit III (COX3) CLIA assay for Antigen Detection
ELT496Hu01 ELISA Kit for Cytochrome C Oxidase Subunit III (COX3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT496Mu01 Recombinant Cytochrome C Oxidase Subunit III (COX3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT496Mu01 Monoclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IP.
PAT496Mu01 Polyclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IF.
Assay Kits CLT496Mu01 CLIA Kit for Cytochrome C Oxidase Subunit III (COX3) CLIA assay for Antigen Detection
ELT496Mu01 ELISA Kit for Cytochrome C Oxidase Subunit III (COX3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT496Ra01 Recombinant Cytochrome C Oxidase Subunit III (COX3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT496Ra01 Monoclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IP.
PAT496Ra01 Polyclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IF.
Assay Kits CLT496Ra01 CLIA Kit for Cytochrome C Oxidase Subunit III (COX3) CLIA assay for Antigen Detection
ELT496Ra01 ELISA Kit for Cytochrome C Oxidase Subunit III (COX3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT496Ca01 Recombinant Cytochrome C Oxidase Subunit III (COX3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT496Ca01 Monoclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IP.
PAT496Ca01 Polyclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IF.
Assay Kits CLT496Ca01 CLIA Kit for Cytochrome C Oxidase Subunit III (COX3) CLIA assay for Antigen Detection
ELT496Ca01 ELISA Kit for Cytochrome C Oxidase Subunit III (COX3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT496Po01 Recombinant Cytochrome C Oxidase Subunit III (COX3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT496Po01 Monoclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IP.
PAT496Po01 Polyclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IF.
Assay Kits CLT496Po01 CLIA Kit for Cytochrome C Oxidase Subunit III (COX3) CLIA assay for Antigen Detection
ELT496Po01 ELISA Kit for Cytochrome C Oxidase Subunit III (COX3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT496Bo01 Recombinant Cytochrome C Oxidase Subunit III (COX3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT496Bo01 Monoclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IP.
PAT496Bo01 Polyclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IF.
Assay Kits CLT496Bo01 CLIA Kit for Cytochrome C Oxidase Subunit III (COX3) CLIA assay for Antigen Detection
ELT496Bo01 ELISA Kit for Cytochrome C Oxidase Subunit III (COX3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT496Rb01 Recombinant Cytochrome C Oxidase Subunit III (COX3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT496Rb01 Monoclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IP.
PAT496Rb01 Polyclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IF.
Assay Kits CLT496Rb01 CLIA Kit for Cytochrome C Oxidase Subunit III (COX3) CLIA assay for Antigen Detection
ELT496Rb01 ELISA Kit for Cytochrome C Oxidase Subunit III (COX3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT496Mo01 Recombinant Cytochrome C Oxidase Subunit III (COX3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT496Mo01 Monoclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IP.
PAT496Mo01 Polyclonal Antibody to Cytochrome C Oxidase Subunit III (COX3) WB; IHC; ICC; IF.
Assay Kits CLT496Mo01 CLIA Kit for Cytochrome C Oxidase Subunit III (COX3) CLIA assay for Antigen Detection
ELT496Mo01 ELISA Kit for Cytochrome C Oxidase Subunit III (COX3) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Sequence and organization of the human mitochondrial genome."
Nature 290:457-465(1981) [PubMed] [Europe PMC] [Abstract]

"In situ origin of deep rooting lineages of mitochondrial Macrohaplogroup 'M' in India."
BMC Genomics 7:151-151(2006) [PubMed] [Europe PMC] [Abstract]

"A MELAS syndrome family harboring two mutations in mitochondrial genome."
Exp. Mol. Med. 40:354-360(2008) [PubMed] [Europe PMC] [Abstract]

"Normal variants of human mitochondrial DNA and translation products: the building of a reference data base."
Hum. Genet. 88:139-145(1991) [PubMed] [Europe PMC] [Abstract]

"Cytochrome c oxidase mutations in Leber hereditary optic neuropathy."
Biochem. Biophys. Res. Commun. 196:810-815(1993) [PubMed] [Europe PMC] [Abstract]

"A new mutation associated with MELAS is located in a mitochondrial DNA polypeptide-coding gene."
Neuromuscul. Disord. 5:391-398(1995) [PubMed] [Europe PMC] [Abstract]

"A microdeletion in cytochrome c oxidase (COX) subunit III associated with COX deficiency and recurrent myoglobinuria."
Nat. Genet. 12:410-416(1996) [PubMed] [Europe PMC] [Abstract]

"Automating the identification of DNA variations using quality-based fluorescence re-sequencing: analysis of the human mitochondrial genome."
Nucleic Acids Res. 26:967-973(1998) [PubMed] [Europe PMC] [Abstract]