Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1)
COX4; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
COX is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. COX4I1 is the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT495Hu01 | Recombinant Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT495Hu01 | Monoclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IP. |
| PAT495Hu01 | Polyclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT495Hu01 | CLIA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | CLIA assay for Antigen Detection |
| ELT495Hu01 | ELISA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT495Mu01 | Recombinant Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT495Mu01 | Monoclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IP. |
| PAT495Mu01 | Polyclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT495Mu01 | CLIA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | CLIA assay for Antigen Detection |
| ELT495Mu01 | ELISA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT495Ra01 | Recombinant Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT495Ra01 | Monoclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IP. |
| PAT495Ra01 | Polyclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT495Ra01 | CLIA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | CLIA assay for Antigen Detection |
| ELT495Ra01 | ELISA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT495Ca01 | Recombinant Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT495Ca01 | Monoclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IP. |
| PAT495Ca01 | Polyclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT495Ca01 | CLIA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | CLIA assay for Antigen Detection |
| ELT495Ca01 | ELISA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT495Po01 | Recombinant Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT495Po01 | Monoclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IP. |
| PAT495Po01 | Polyclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT495Po01 | CLIA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | CLIA assay for Antigen Detection |
| ELT495Po01 | ELISA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT495Bo01 | Recombinant Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT495Bo01 | Monoclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IP. |
| PAT495Bo01 | Polyclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT495Bo01 | CLIA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | CLIA assay for Antigen Detection |
| ELT495Bo01 | ELISA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT495Rb01 | Recombinant Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT495Rb01 | Monoclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IP. |
| PAT495Rb01 | Polyclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT495Rb01 | CLIA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | CLIA assay for Antigen Detection |
| ELT495Rb01 | ELISA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT495Mo01 | Recombinant Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT495Mo01 | Monoclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IP. |
| PAT495Mo01 | Polyclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT495Mo01 | CLIA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | CLIA assay for Antigen Detection |
| ELT495Mo01 | ELISA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Isolation of a cDNA clone encoding subunit IV of human cytochrome c oxidase."
Gene 55:205-217(1987) [PubMed] [Europe PMC] [Abstract]
"Novel use of a chimpanzee pseudogene for chromosomal mapping of human cytochrome c oxidase subunit IV."
Gene 86:209-216(1990) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"The 5-prime region of the COX4 gene contains a novel overlapping gene, NOC4."
Mamm. Genome 10:506-512(1999) [PubMed] [Europe PMC] [Abstract]
"Subunit IV of human cytochrome c oxidase, polymorphism and a putative isoform."
Biochim. Biophys. Acta 1119:218-224(1992) [PubMed] [Europe PMC] [Abstract]
"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]