Phosphofructokinase, Muscle (PFKM)
PFK1; PFKX; Phosphofructokinase 1; Phosphofructo-1-kinase isozyme A; 6-Phosphofructokinase Polypeptide X; Fructose-6-Phosphate 1-Phosphotransferase
- Phosphofructokinase-1 (PFK-1) is the most important regulatory enzyme (EC 2.7.1.11) of glycolysis. It is an allosteric enzyme made of 4 subunits and controlled by several activators and inhibitors. PFK-1 catalyzes one of the important "committed" steps of glycolysis, the conversion of fructose 6-phosphate and ATP to fructose 1,6-bisphosphate and ADP.
- PFK1 is allosterically inhibited by ATP and citrate (from the citric acid cycle) and its product. It is also inhibited by low pH to prevent the accumulation of hydrogen ions in muscle. The enzyme has two sites with different affinities for ATP which is both a substrate and an inhibitor.PFK1 is allosterically activated by a high concentration of AMP, but the most potent activator is fructose 2,6-bisphosphate, which is also produced from fructose-6-phosphate by PFK2.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT377Hu01 | Recombinant Phosphofructokinase, Muscle (PFKM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT377Hu01 | Monoclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IP. |
| PAT377Hu01 | Polyclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT377Hu01 | CLIA Kit for Phosphofructokinase, Muscle (PFKM) | CLIA assay for Antigen Detection |
| ELT377Hu01 | ELISA Kit for Phosphofructokinase, Muscle (PFKM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT377Mu01 | Recombinant Phosphofructokinase, Muscle (PFKM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT377Mu01 | Monoclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IP. |
| PAT377Mu01 | Polyclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT377Mu01 | CLIA Kit for Phosphofructokinase, Muscle (PFKM) | CLIA assay for Antigen Detection |
| ELT377Mu01 | ELISA Kit for Phosphofructokinase, Muscle (PFKM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT377Ra01 | Recombinant Phosphofructokinase, Muscle (PFKM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT377Ra01 | Monoclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IP. |
| PAT377Ra01 | Polyclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT377Ra01 | CLIA Kit for Phosphofructokinase, Muscle (PFKM) | CLIA assay for Antigen Detection |
| ELT377Ra01 | ELISA Kit for Phosphofructokinase, Muscle (PFKM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT377Ca01 | Recombinant Phosphofructokinase, Muscle (PFKM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT377Ca01 | Monoclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IP. |
| PAT377Ca01 | Polyclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT377Ca01 | CLIA Kit for Phosphofructokinase, Muscle (PFKM) | CLIA assay for Antigen Detection |
| ELT377Ca01 | ELISA Kit for Phosphofructokinase, Muscle (PFKM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT377Po01 | Recombinant Phosphofructokinase, Muscle (PFKM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT377Po01 | Monoclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IP. |
| PAT377Po01 | Polyclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT377Po01 | CLIA Kit for Phosphofructokinase, Muscle (PFKM) | CLIA assay for Antigen Detection |
| ELT377Po01 | ELISA Kit for Phosphofructokinase, Muscle (PFKM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT377Bo01 | Recombinant Phosphofructokinase, Muscle (PFKM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT377Bo01 | Monoclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IP. |
| PAT377Bo01 | Polyclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT377Bo01 | CLIA Kit for Phosphofructokinase, Muscle (PFKM) | CLIA assay for Antigen Detection |
| ELT377Bo01 | ELISA Kit for Phosphofructokinase, Muscle (PFKM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT377Rb01 | Recombinant Phosphofructokinase, Muscle (PFKM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT377Rb01 | Monoclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IP. |
| PAT377Rb01 | Polyclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT377Rb01 | CLIA Kit for Phosphofructokinase, Muscle (PFKM) | CLIA assay for Antigen Detection |
| ELT377Rb01 | ELISA Kit for Phosphofructokinase, Muscle (PFKM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT377Mo01 | Recombinant Phosphofructokinase, Muscle (PFKM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT377Mo01 | Monoclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IP. |
| PAT377Mo01 | Polyclonal Antibody to Phosphofructokinase, Muscle (PFKM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT377Mo01 | CLIA Kit for Phosphofructokinase, Muscle (PFKM) | CLIA assay for Antigen Detection |
| ELT377Mo01 | ELISA Kit for Phosphofructokinase, Muscle (PFKM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Front. Physiol. 4:393-393(2013) [PubMed] [Europe PMC] [Abstract]