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Heat Shock Protein 90kDa Alpha B1 (HSP90aB1)

HSP90-BETA; HSP90B; HSPC2; HSPCB; HSP84; Heat Shock 90kD Protein 1,Beta; Heat shock 84 kDa

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1) and mitochondria (TRAP1).Like other HSP90 proteins, the 724-amino acid HSP90AB1 protein has a highly conserved N-terminal domain, a charged domain, a middle domain involved in ATPase activity, a second charged domain, and a C-terminal domain. It also has a 4-helical cytokine motif, a gln-rich region, and a C-terminal MEEVD motif characteristic of cytosolic HSP90 proteins.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT261Hu01 Recombinant Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT261Hu01 Monoclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IP.
PAT261Hu01 Polyclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IF.
Assay Kits CLT261Hu01 CLIA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) CLIA assay for Antigen Detection
ELT261Hu01 ELISA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT261Mu01 Recombinant Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT261Mu01 Monoclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IP.
PAT261Mu01 Polyclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IF.
Assay Kits CLT261Mu01 CLIA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) CLIA assay for Antigen Detection
ELT261Mu01 ELISA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT261Ra01 Recombinant Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT261Ra01 Monoclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IP.
PAT261Ra01 Polyclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IF.
Assay Kits CLT261Ra01 CLIA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) CLIA assay for Antigen Detection
ELT261Ra01 ELISA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT261Ca01 Recombinant Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT261Ca01 Monoclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IP.
PAT261Ca01 Polyclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IF.
Assay Kits CLT261Ca01 CLIA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) CLIA assay for Antigen Detection
ELT261Ca01 ELISA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT261Po01 Recombinant Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT261Po01 Monoclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IP.
PAT261Po01 Polyclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IF.
Assay Kits CLT261Po01 CLIA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) CLIA assay for Antigen Detection
ELT261Po01 ELISA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT261Bo01 Recombinant Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT261Bo01 Monoclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IP.
PAT261Bo01 Polyclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IF.
Assay Kits CLT261Bo01 CLIA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) CLIA assay for Antigen Detection
ELT261Bo01 ELISA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT261Rb01 Recombinant Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT261Rb01 Monoclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IP.
PAT261Rb01 Polyclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IF.
Assay Kits CLT261Rb01 CLIA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) CLIA assay for Antigen Detection
ELT261Rb01 ELISA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT261Mo01 Recombinant Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT261Mo01 Monoclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IP.
PAT261Mo01 Polyclonal Antibody to Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) WB; IHC; ICC; IF.
Assay Kits CLT261Mo01 CLIA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) CLIA assay for Antigen Detection
ELT261Mo01 ELISA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Nucleotide sequence of a cDNA for a member of the human 90-kDa heat-shock protein family."
Gene 53:235-245(1987) [PubMed] [Europe PMC] [Abstract]

"Nucleotide sequence and regulation of a human 90-kDa heat shock protein gene."
J. Biol. Chem. 264:15006-15011(1989) [PubMed] [Europe PMC] [Abstract]

"Heat-shock proteins, Hsp84 and Hsp86, of mice and men: two related genes encode formerly identified tumour-specific transplantation antigens."
Gene 74:491-501(1988) [PubMed] [Europe PMC] [Abstract]

"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Two human 90-kDa heat shock proteins are phosphorylated in vivo at conserved serines that are phosphorylated in vitro by casein kinase II."
J. Biol. Chem. 264:2431-2437(1989) [PubMed] [Europe PMC] [Abstract]