ATP Binding Cassette Transporter B8 (ABCB8)
ABC-B8; M-ABC1; MABC1; Mitochondrial ABC Protein; Mitochondrial ATP-binding cassette 1; ATP-binding cassette sub-family B member 8, mitochondrial
ATP-binding cassette sub-family B member 8, mitochondrial is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT146Hu01 | Recombinant ATP Binding Cassette Transporter B8 (ABCB8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT146Hu01 | Monoclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IP. |
| PAT146Hu01 | Polyclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT146Hu01 | CLIA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | CLIA assay for Antigen Detection |
| ELT146Hu01 | ELISA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT146Mu01 | Recombinant ATP Binding Cassette Transporter B8 (ABCB8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT146Mu01 | Monoclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IP. |
| PAT146Mu01 | Polyclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT146Mu01 | CLIA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | CLIA assay for Antigen Detection |
| ELT146Mu01 | ELISA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT146Ra01 | Recombinant ATP Binding Cassette Transporter B8 (ABCB8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT146Ra01 | Monoclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IP. |
| PAT146Ra01 | Polyclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT146Ra01 | CLIA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | CLIA assay for Antigen Detection |
| ELT146Ra01 | ELISA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT146Ca01 | Recombinant ATP Binding Cassette Transporter B8 (ABCB8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT146Ca01 | Monoclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IP. |
| PAT146Ca01 | Polyclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT146Ca01 | CLIA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | CLIA assay for Antigen Detection |
| ELT146Ca01 | ELISA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT146Po01 | Recombinant ATP Binding Cassette Transporter B8 (ABCB8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT146Po01 | Monoclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IP. |
| PAT146Po01 | Polyclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT146Po01 | CLIA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | CLIA assay for Antigen Detection |
| ELT146Po01 | ELISA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT146Bo01 | Recombinant ATP Binding Cassette Transporter B8 (ABCB8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT146Bo01 | Monoclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IP. |
| PAT146Bo01 | Polyclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT146Bo01 | CLIA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | CLIA assay for Antigen Detection |
| ELT146Bo01 | ELISA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT146Rb01 | Recombinant ATP Binding Cassette Transporter B8 (ABCB8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT146Rb01 | Monoclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IP. |
| PAT146Rb01 | Polyclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT146Rb01 | CLIA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | CLIA assay for Antigen Detection |
| ELT146Rb01 | ELISA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT146Mo01 | Recombinant ATP Binding Cassette Transporter B8 (ABCB8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT146Mo01 | Monoclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IP. |
| PAT146Mo01 | Polyclonal Antibody to ATP Binding Cassette Transporter B8 (ABCB8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT146Mo01 | CLIA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | CLIA assay for Antigen Detection |
| ELT146Mo01 | ELISA Kit for ATP Binding Cassette Transporter B8 (ABCB8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein."
J. Mol. Biol. 285:379-389(1999) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of human chromosome 7."
Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Targeting of the mitochondrial membrane proteins to the cell surface for functional studies."
Biochem. Biophys. Res. Commun. 338:1143-1151(2005) [PubMed] [Europe PMC] [Abstract]
"Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population."
J. Hum. Genet. 47:38-50(2002) [PubMed] [Europe PMC] [Abstract]
"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]