Regulator Of G Protein Signaling 5 (RGS5)
The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. Multiple genes homologous to SST2 are present in higher eukaryotes. RGS proteins are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. The amino acid sequence deduced from the cDNA possessed all consensus motifs of the RGS domain and showed closest homology to mouse Rgs5, with which it was 90% identical, indicating that it represented human RGS5. The mRNA of the human gene is abundantly expressed in heart, lung, skeletal muscle, and small intestine, and at low levels in brain, placenta, liver, colon, and leukocytes.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT079Hu01 | Recombinant Regulator Of G Protein Signaling 5 (RGS5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT079Hu01 | Monoclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IP. |
| PAT079Hu01 | Polyclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT079Hu01 | CLIA Kit for Regulator Of G Protein Signaling 5 (RGS5) | CLIA assay for Antigen Detection |
| ELT079Hu01 | ELISA Kit for Regulator Of G Protein Signaling 5 (RGS5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT079Mu01 | Recombinant Regulator Of G Protein Signaling 5 (RGS5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT079Mu01 | Monoclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IP. |
| PAT079Mu01 | Polyclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT079Mu01 | CLIA Kit for Regulator Of G Protein Signaling 5 (RGS5) | CLIA assay for Antigen Detection |
| ELT079Mu01 | ELISA Kit for Regulator Of G Protein Signaling 5 (RGS5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT079Ra01 | Recombinant Regulator Of G Protein Signaling 5 (RGS5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT079Ra01 | Monoclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IP. |
| PAT079Ra01 | Polyclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT079Ra01 | CLIA Kit for Regulator Of G Protein Signaling 5 (RGS5) | CLIA assay for Antigen Detection |
| ELT079Ra01 | ELISA Kit for Regulator Of G Protein Signaling 5 (RGS5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT079Ca01 | Recombinant Regulator Of G Protein Signaling 5 (RGS5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT079Ca01 | Monoclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IP. |
| PAT079Ca01 | Polyclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT079Ca01 | CLIA Kit for Regulator Of G Protein Signaling 5 (RGS5) | CLIA assay for Antigen Detection |
| ELT079Ca01 | ELISA Kit for Regulator Of G Protein Signaling 5 (RGS5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT079Po01 | Recombinant Regulator Of G Protein Signaling 5 (RGS5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT079Po01 | Monoclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IP. |
| PAT079Po01 | Polyclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT079Po01 | CLIA Kit for Regulator Of G Protein Signaling 5 (RGS5) | CLIA assay for Antigen Detection |
| ELT079Po01 | ELISA Kit for Regulator Of G Protein Signaling 5 (RGS5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT079Bo01 | Recombinant Regulator Of G Protein Signaling 5 (RGS5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT079Bo01 | Monoclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IP. |
| PAT079Bo01 | Polyclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT079Bo01 | CLIA Kit for Regulator Of G Protein Signaling 5 (RGS5) | CLIA assay for Antigen Detection |
| ELT079Bo01 | ELISA Kit for Regulator Of G Protein Signaling 5 (RGS5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT079Rb01 | Recombinant Regulator Of G Protein Signaling 5 (RGS5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT079Rb01 | Monoclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IP. |
| PAT079Rb01 | Polyclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT079Rb01 | CLIA Kit for Regulator Of G Protein Signaling 5 (RGS5) | CLIA assay for Antigen Detection |
| ELT079Rb01 | ELISA Kit for Regulator Of G Protein Signaling 5 (RGS5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT079Mo01 | Recombinant Regulator Of G Protein Signaling 5 (RGS5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT079Mo01 | Monoclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IP. |
| PAT079Mo01 | Polyclonal Antibody to Regulator Of G Protein Signaling 5 (RGS5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT079Mo01 | CLIA Kit for Regulator Of G Protein Signaling 5 (RGS5) | CLIA assay for Antigen Detection |
| ELT079Mo01 | ELISA Kit for Regulator Of G Protein Signaling 5 (RGS5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Isolation, tissue expression, and chromosomal assignment of human RGS5, a novel G-protein signaling regulator gene."
J. Hum. Genet. 43:202-205(1998) [PubMed] [Europe PMC] [Abstract]
"Genetic screens in yeast to identify mammalian nonreceptor modulators of G-protein signaling."
Nat. Biotechnol. 17:878-883(1999) [PubMed] [Europe PMC] [Abstract]
"Identification of a novel alternative splicing variant of RGS5 mRNA in human ocular tissues."
FEBS J. 272:791-799(2005) [PubMed] [Europe PMC] [Abstract]
"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Solution structure of the RGS domain of regulator of G-protein signalling 5 (RGS 5)."
Submitted (NOV-2005) to the PDB data bank