Phospholipase C Eta 1 (PLCh1)
PLCL3; PLCeta1; Phospholipase C-Like 3; Phosphoinositide phospholipase C-eta-1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1
The deduced 1,002-amino acid PLCH1 isoform has a calculated molecular mass of 115 kD and shares similarity with other PLC family members. Northern blot analysis of human tissues detected a 7.4-kb transcript in brain and lung. Western blot analysis of mouse tissues detected Plch1 protein exclusively in nerve tissues such as cerebrum, cerebellum, and the spinal cord. In contrast to the mRNA data, Plch1 protein was not detected in lung. In situ hybridization detected mouse Plch1 mRNA expression throughout the brain with high expression in neuronal, cell-enriched regions. Fluorescence microscopy of HEK293 cells localized PLCH1 to the cytosol and membrane but not in the nucleus; in mouse brain tissues, Plch1 was detected in all cytosolic and membrane fractions.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS930Hu01 | Recombinant Phospholipase C Eta 1 (PLCh1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS930Hu01 | Monoclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IP. |
| PAS930Hu01 | Polyclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS930Hu01 | CLIA Kit for Phospholipase C Eta 1 (PLCh1) | CLIA assay for Antigen Detection |
| ELS930Hu01 | ELISA Kit for Phospholipase C Eta 1 (PLCh1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS930Mu01 | Recombinant Phospholipase C Eta 1 (PLCh1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS930Mu01 | Monoclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IP. |
| PAS930Mu01 | Polyclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS930Mu01 | CLIA Kit for Phospholipase C Eta 1 (PLCh1) | CLIA assay for Antigen Detection |
| ELS930Mu01 | ELISA Kit for Phospholipase C Eta 1 (PLCh1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS930Ra01 | Recombinant Phospholipase C Eta 1 (PLCh1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS930Ra01 | Monoclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IP. |
| PAS930Ra01 | Polyclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS930Ra01 | CLIA Kit for Phospholipase C Eta 1 (PLCh1) | CLIA assay for Antigen Detection |
| ELS930Ra01 | ELISA Kit for Phospholipase C Eta 1 (PLCh1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS930Ca01 | Recombinant Phospholipase C Eta 1 (PLCh1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS930Ca01 | Monoclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IP. |
| PAS930Ca01 | Polyclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS930Ca01 | CLIA Kit for Phospholipase C Eta 1 (PLCh1) | CLIA assay for Antigen Detection |
| ELS930Ca01 | ELISA Kit for Phospholipase C Eta 1 (PLCh1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS930Po01 | Recombinant Phospholipase C Eta 1 (PLCh1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS930Po01 | Monoclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IP. |
| PAS930Po01 | Polyclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS930Po01 | CLIA Kit for Phospholipase C Eta 1 (PLCh1) | CLIA assay for Antigen Detection |
| ELS930Po01 | ELISA Kit for Phospholipase C Eta 1 (PLCh1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS930Bo01 | Recombinant Phospholipase C Eta 1 (PLCh1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS930Bo01 | Monoclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IP. |
| PAS930Bo01 | Polyclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS930Bo01 | CLIA Kit for Phospholipase C Eta 1 (PLCh1) | CLIA assay for Antigen Detection |
| ELS930Bo01 | ELISA Kit for Phospholipase C Eta 1 (PLCh1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS930Rb01 | Recombinant Phospholipase C Eta 1 (PLCh1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS930Rb01 | Monoclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IP. |
| PAS930Rb01 | Polyclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS930Rb01 | CLIA Kit for Phospholipase C Eta 1 (PLCh1) | CLIA assay for Antigen Detection |
| ELS930Rb01 | ELISA Kit for Phospholipase C Eta 1 (PLCh1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS930Mo01 | Recombinant Phospholipase C Eta 1 (PLCh1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS930Mo01 | Monoclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IP. |
| PAS930Mo01 | Polyclonal Antibody to Phospholipase C Eta 1 (PLCh1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS930Mo01 | CLIA Kit for Phospholipase C Eta 1 (PLCh1) | CLIA assay for Antigen Detection |
| ELS930Mo01 | ELISA Kit for Phospholipase C Eta 1 (PLCh1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Molecular cloning and characterization of a novel phospholipase C, PLC-eta."
Biochem. J. 389:181-186(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]