Phosphoserine Aminotransferase 1 (PSAT1)
PSA; EPIP; Endometrial Progesterone Induced Protein; Phosphohydroxythreonine aminotransferase
PSAT catalyzes the second step in the pathway, conversion of 3-phosphohydroxypyruvate into 3-phosphoserine. The full-length PSAT-beta transcript encodes a deduced 370-amino acid protein with a calculated molecular mass of 40 kD. PSAT-alpha lacks exon 8 and encodes a deduced 324-amino acid protein with a calculated molecular mass of 35.2 kD. Compared with PSAT-beta, PSAT-alpha lacks 46 amino acids. Both proteins contain a conserved binding domain for the cofactor pyridoxal 5-prime-phosphate (vitamin B6). PSAT-beta shares 92.4% amino acid similarity with its mouse homolog. PSAT-beta orthologs were present in all species examined, including plants, insects, and bacteria.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS913Hu01 | Recombinant Phosphoserine Aminotransferase 1 (PSAT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS913Hu01 | Monoclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IP. |
| PAS913Hu01 | Polyclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS913Hu01 | CLIA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | CLIA assay for Antigen Detection |
| ELS913Hu01 | ELISA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS913Mu01 | Recombinant Phosphoserine Aminotransferase 1 (PSAT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS913Mu01 | Monoclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IP. |
| PAS913Mu01 | Polyclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS913Mu01 | CLIA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | CLIA assay for Antigen Detection |
| ELS913Mu01 | ELISA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS913Ra01 | Recombinant Phosphoserine Aminotransferase 1 (PSAT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS913Ra01 | Monoclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IP. |
| PAS913Ra01 | Polyclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS913Ra01 | CLIA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | CLIA assay for Antigen Detection |
| ELS913Ra01 | ELISA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS913Ca01 | Recombinant Phosphoserine Aminotransferase 1 (PSAT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS913Ca01 | Monoclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IP. |
| PAS913Ca01 | Polyclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS913Ca01 | CLIA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | CLIA assay for Antigen Detection |
| ELS913Ca01 | ELISA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS913Po01 | Recombinant Phosphoserine Aminotransferase 1 (PSAT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS913Po01 | Monoclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IP. |
| PAS913Po01 | Polyclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS913Po01 | CLIA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | CLIA assay for Antigen Detection |
| ELS913Po01 | ELISA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS913Bo01 | Recombinant Phosphoserine Aminotransferase 1 (PSAT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS913Bo01 | Monoclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IP. |
| PAS913Bo01 | Polyclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS913Bo01 | CLIA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | CLIA assay for Antigen Detection |
| ELS913Bo01 | ELISA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS913Rb01 | Recombinant Phosphoserine Aminotransferase 1 (PSAT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS913Rb01 | Monoclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IP. |
| PAS913Rb01 | Polyclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS913Rb01 | CLIA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | CLIA assay for Antigen Detection |
| ELS913Rb01 | ELISA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS913Mo01 | Recombinant Phosphoserine Aminotransferase 1 (PSAT1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS913Mo01 | Monoclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IP. |
| PAS913Mo01 | Polyclonal Antibody to Phosphoserine Aminotransferase 1 (PSAT1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS913Mo01 | CLIA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | CLIA assay for Antigen Detection |
| ELS913Mo01 | ELISA Kit for Phosphoserine Aminotransferase 1 (PSAT1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Characterization of human phosphoserine aminotransferase involved in the phosphorylated pathway of L-serine biosynthesis."
Biochem. J. 373:191-200(2003) [PubMed] [Europe PMC] [Abstract]
"DNA sequence and analysis of human chromosome 9."
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Phosphoserine aminotransferase deficiency: a novel disorder of the serine biosynthesis pathway."
Am. J. Hum. Genet. 80:931-937(2007) [PubMed] [Europe PMC] [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"Neu-Laxova syndrome is a heterogeneous metabolic disorder caused by defects in enzymes of the L-serine biosynthesis pathway."
Am. J. Hum. Genet. 95:285-293(2014) [PubMed] [Europe PMC] [Abstract]