Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9)
CDw329; CD329; OBBP-LIKE; Protein FOAP-9
SIGLEC9 has 8 potential N-linked glycosylation sites and a cytoplasmic tail with 94 residues. Unlike SIGLEC7, COS cells expressing SIGLEC9 required sialidase treatment before binding to red cells, which must not be treated with the enzyme. Northern blot analysis detected clear expression in spleen and placenta, with low or undetectable expression in liver, colon, stomach, and testis. Flow cytometric analysis demonstrated expression on monocytes and neutrophils, as well as on a subpopulation of lymphocytes, but not on eosinophils.SIGLEC9 binding to erythrocytes could be abolished by sialidase treatment of the red cells. SIGLEC9 was found to bind to both alpha-2-3- and alpha-2-6-linked sialic acids. Unlike other Ig-like genes, no SIGLEC homologs were identified in the C. elegans and fruit fly databases.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS866Hu01 | Recombinant Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS866Hu01 | Monoclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IP. |
| PAS866Hu01 | Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS866Hu01 | CLIA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | CLIA assay for Antigen Detection |
| ELS866Hu01 | ELISA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS866Mu01 | Recombinant Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS866Mu01 | Monoclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IP. |
| PAS866Mu01 | Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS866Mu01 | CLIA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | CLIA assay for Antigen Detection |
| ELS866Mu01 | ELISA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS866Ra01 | Recombinant Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS866Ra01 | Monoclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IP. |
| PAS866Ra01 | Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS866Ra01 | CLIA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | CLIA assay for Antigen Detection |
| ELS866Ra01 | ELISA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS866Ca01 | Recombinant Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS866Ca01 | Monoclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IP. |
| PAS866Ca01 | Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS866Ca01 | CLIA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | CLIA assay for Antigen Detection |
| ELS866Ca01 | ELISA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS866Po01 | Recombinant Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS866Po01 | Monoclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IP. |
| PAS866Po01 | Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS866Po01 | CLIA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | CLIA assay for Antigen Detection |
| ELS866Po01 | ELISA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS866Bo01 | Recombinant Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS866Bo01 | Monoclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IP. |
| PAS866Bo01 | Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS866Bo01 | CLIA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | CLIA assay for Antigen Detection |
| ELS866Bo01 | ELISA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS866Rb01 | Recombinant Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS866Rb01 | Monoclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IP. |
| PAS866Rb01 | Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS866Rb01 | CLIA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | CLIA assay for Antigen Detection |
| ELS866Rb01 | ELISA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS866Mo01 | Recombinant Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS866Mo01 | Monoclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IP. |
| PAS866Mo01 | Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS866Mo01 | CLIA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | CLIA assay for Antigen Detection |
| ELS866Mo01 | ELISA Kit for Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Identification and molecular characterization of a novel member of the siglec family (SIGLEC9)."
Genomics 67:171-178(2000) [PubMed] [Europe PMC] [Abstract]
"Siglec-9, a novel sialic acid binding member of the immunoglobulin superfamily expressed broadly on human blood leukocytes."
J. Biol. Chem. 275:22121-22126(2000) [PubMed] [Europe PMC] [Abstract]
"Cloning, characterization, and phylogenetic analysis of siglec-9, a new member of the CD33-related group of siglecs. Evidence for co-evolution with sialic acid synthesis pathways."
J. Biol. Chem. 275:22127-22135(2000) [PubMed] [Europe PMC] [Abstract]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biology of human chromosome 19."
Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]