Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1)
THRA1; EAR1; THRAL; ear-1; hRev; Rev-ErbA Alpha; V-erbA-related protein 1
- Rev-erbα is highly expressed in the liver, skeletal muscle, adipose tissue, and the brain, participating in the development and circadian regulation of these tissues.
- Rev-erbα is transcribed from the opposite strand of the thyroid receptor α (c-erbAα) gene on chromosome 17, with a 269-nucleotide overlap between the two transcripts. The other mammalian isoform of the receptor, Rev-erbβ is encoded by another gene on chromosome 3. In addition, there is one non-mammalian homolog, the ecdysone-regulated gene E75, which is present in Drosophila and C. elegans.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS844Hu01 | Recombinant Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS844Hu01 | Monoclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IP. |
| PAS844Hu01 | Polyclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS844Hu01 | CLIA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | CLIA assay for Antigen Detection |
| ELS844Hu01 | ELISA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS844Mu01 | Recombinant Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS844Mu01 | Monoclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IP. |
| PAS844Mu01 | Polyclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS844Mu01 | CLIA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | CLIA assay for Antigen Detection |
| ELS844Mu01 | ELISA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS844Ra01 | Recombinant Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS844Ra01 | Monoclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IP. |
| PAS844Ra01 | Polyclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS844Ra01 | CLIA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | CLIA assay for Antigen Detection |
| ELS844Ra01 | ELISA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS844Ca01 | Recombinant Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS844Ca01 | Monoclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IP. |
| PAS844Ca01 | Polyclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS844Ca01 | CLIA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | CLIA assay for Antigen Detection |
| ELS844Ca01 | ELISA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS844Po01 | Recombinant Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS844Po01 | Monoclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IP. |
| PAS844Po01 | Polyclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS844Po01 | CLIA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | CLIA assay for Antigen Detection |
| ELS844Po01 | ELISA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS844Bo01 | Recombinant Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS844Bo01 | Monoclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IP. |
| PAS844Bo01 | Polyclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS844Bo01 | CLIA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | CLIA assay for Antigen Detection |
| ELS844Bo01 | ELISA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS844Rb01 | Recombinant Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS844Rb01 | Monoclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IP. |
| PAS844Rb01 | Polyclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS844Rb01 | CLIA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | CLIA assay for Antigen Detection |
| ELS844Rb01 | ELISA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS844Mo01 | Recombinant Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS844Mo01 | Monoclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IP. |
| PAS844Mo01 | Polyclonal Antibody to Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS844Mo01 | CLIA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | CLIA assay for Antigen Detection |
| ELS844Mo01 | ELISA Kit for Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Two erbA homologs encoding proteins with different T3 binding capacities are transcribed from opposite DNA strands of the same genetic locus."
Cell 57:31-39(1989) [PubMed] [Europe PMC] [Abstract]
"Isolation of a cDNA encoding human Rev-ErbA alpha: transcription from the noncoding DNA strand of a thyroid hormone receptor gene results in a related protein that does not bind thyroid hormone."
DNA Cell Biol. 9:77-83(1990) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Genomic organization of the human thyroid hormone receptor alpha (c-erbA-1) gene."
Nucleic Acids Res. 19:1105-1112(1991) [PubMed] [Europe PMC] [Abstract]
"Orphan nuclear hormone receptor Rev-erbalpha regulates the human apolipoprotein CIII promoter."
J. Biol. Chem. 277:27120-27129(2002) [PubMed] [Europe PMC] [Abstract]
"The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene."
Mol. Endocrinol. 19:1452-1459(2005) [PubMed] [Europe PMC] [Abstract]
"The orphan nuclear receptor Rev-erb alpha regulates circadian expression of plasminogen activator inhibitor type 1."
J. Biol. Chem. 281:33842-33848(2006) [PubMed] [Europe PMC] [Abstract]
"Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock."
Science 311:1002-1005(2006) [PubMed] [Europe PMC] [Abstract]
"A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription."
FEBS J. 274:5370-5381(2007) [PubMed] [Europe PMC] [Abstract]
"Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways."
Science 318:1786-1789(2007) [PubMed] [Europe PMC] [Abstract]
"Negative feedback maintenance of heme homeostasis by its receptor, Rev-erbalpha."
Genes Dev. 23:2201-2209(2009) [PubMed] [Europe PMC] [Abstract]
"Nuclear receptor Rev-erbalpha: a heme receptor that coordinates circadian rhythm and metabolism."
Nucl. Recept. Signal. 8:E001-E001(2010) [PubMed] [Europe PMC] [Abstract]
"A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbalpha."
Nat. Neurosci. 14:1293-1301(2011) [PubMed] [Europe PMC] [Abstract]
"Cryptochromes mediate rhythmic repression of the glucocorticoid receptor."
Nature 480:552-556(2011) [PubMed] [Europe PMC] [Abstract]
"Direct regulation of CLOCK expression by REV-ERB."
PLoS ONE 6:E17290-E17290(2011) [PubMed] [Europe PMC] [Abstract]
"REV-ERBs: more than the sum of the individual parts."
Cell Metab. 15:791-793(2012) [PubMed] [Europe PMC] [Abstract]
"REV-ERB-erating nuclear receptor functions in circadian metabolism and physiology."
Cell Res. 22:1319-1321(2012) [PubMed] [Europe PMC] [Abstract]
"The nuclear receptor REV-ERBalpha mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines."
Proc. Natl. Acad. Sci. U.S.A. 109:582-587(2012) [PubMed] [Europe PMC] [Abstract]
"DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbalpha."
Biochem. J. 451:453-461(2013) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"Structural elements of an orphan nuclear receptor-DNA complex."
Mol. Cell 1:849-861(1998) [PubMed] [Europe PMC] [Abstract]