Procollagen C Proteinase Enhancer 2 (PCPE2)
PCOLCE2; Procollagen C Endopeptidase Enhancer 2; Procollagen COOH-terminal proteinase enhancer 2
PCOLCE2 lies 5.2 kb and 102.5 kb centromeric to the transient receptor potential channel-1 (TRPC1) and plastin-1 (PLS1), respectively. The deduced 415-amino acid protein contains an N-terminal signal sequence, 2 CUB domains, and an NTR domain. It also contains a putative myristoylation site, several potential phosphorylation sites, a putative glycosylation site, and an RGD site. PCOLCE2 shares about 43% sequence identity with the PCOLCE protein .
The secreted PCOLCE2 protein is calculated to have a molecular mass of about 47 kD. Northern blot analysis detected ubiquitous expression of a 2-kb transcript, with highest expression in heart, placenta, and trabecular meshwork, and very low expression in brain. Western blot analysis revealed a 52-kD form of PCOLCE2 in human fibroblast cells.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS793Hu01 | Recombinant Procollagen C Proteinase Enhancer 2 (PCPE2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS793Hu01 | Monoclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IP. |
| PAS793Hu01 | Polyclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS793Hu01 | CLIA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | CLIA assay for Antigen Detection |
| ELS793Hu01 | ELISA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS793Mu01 | Recombinant Procollagen C Proteinase Enhancer 2 (PCPE2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS793Mu01 | Monoclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IP. |
| PAS793Mu01 | Polyclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS793Mu01 | CLIA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | CLIA assay for Antigen Detection |
| ELS793Mu01 | ELISA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS793Ra01 | Recombinant Procollagen C Proteinase Enhancer 2 (PCPE2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS793Ra01 | Monoclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IP. |
| PAS793Ra01 | Polyclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS793Ra01 | CLIA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | CLIA assay for Antigen Detection |
| ELS793Ra01 | ELISA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS793Ca01 | Recombinant Procollagen C Proteinase Enhancer 2 (PCPE2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS793Ca01 | Monoclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IP. |
| PAS793Ca01 | Polyclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS793Ca01 | CLIA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | CLIA assay for Antigen Detection |
| ELS793Ca01 | ELISA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS793Po01 | Recombinant Procollagen C Proteinase Enhancer 2 (PCPE2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS793Po01 | Monoclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IP. |
| PAS793Po01 | Polyclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS793Po01 | CLIA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | CLIA assay for Antigen Detection |
| ELS793Po01 | ELISA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS793Bo01 | Recombinant Procollagen C Proteinase Enhancer 2 (PCPE2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS793Bo01 | Monoclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IP. |
| PAS793Bo01 | Polyclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS793Bo01 | CLIA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | CLIA assay for Antigen Detection |
| ELS793Bo01 | ELISA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS793Rb01 | Recombinant Procollagen C Proteinase Enhancer 2 (PCPE2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS793Rb01 | Monoclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IP. |
| PAS793Rb01 | Polyclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS793Rb01 | CLIA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | CLIA assay for Antigen Detection |
| ELS793Rb01 | ELISA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS793Mo01 | Recombinant Procollagen C Proteinase Enhancer 2 (PCPE2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS793Mo01 | Monoclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IP. |
| PAS793Mo01 | Polyclonal Antibody to Procollagen C Proteinase Enhancer 2 (PCPE2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS793Mo01 | CLIA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | CLIA assay for Antigen Detection |
| ELS793Mo01 | ELISA Kit for Procollagen C Proteinase Enhancer 2 (PCPE2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Identification and expression of a novel type I procollagen C-proteinase enhancer protein gene from the glaucoma candidate region on 3q21-q24."
Genomics 66:264-273(2000) [PubMed] [Europe PMC] [Abstract]
"Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries."
Osteoarthritis Cartilage 9:641-653(2001) [PubMed] [Europe PMC] [Abstract]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
"PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1."
J. Biol. Chem. 277:49820-49830(2002) [PubMed] [Europe PMC] [Abstract]