Lipase Maturation Factor 1 (LMF1)
TMEM112; JFP11; C16orf26; Transmembrane Protein 112
- Lmf1 RNA was expressed at higher levels in tissues that express little or no lipase activity such as testis and pancreas, suggesting that Lmf1 may have additional functions in these tissues. The Lmf1 protein was predicted to contain 5 transmembrane domains and an evolutionarily conserved domain comprising most of the C-terminal end. Colocalization with calnexin demonstrated that the Lmf1 protein is localized to the endoplasmic reticulum (ER).
- The resulting LMF1 truncation, tyr439 to stop (Y439X), removed 127 residues from the C terminus compared with 212 residues eliminated by the cld mutation in the mouse. The Y439X subject showed markedly high plasma triglyceride and had undergone repeated episodes of pancreatitis.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS607Hu01 | Recombinant Lipase Maturation Factor 1 (LMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS607Hu01 | Monoclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IP. |
| PAS607Hu01 | Polyclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS607Hu01 | CLIA Kit for Lipase Maturation Factor 1 (LMF1) | CLIA assay for Antigen Detection |
| ELS607Hu01 | ELISA Kit for Lipase Maturation Factor 1 (LMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS607Mu01 | Recombinant Lipase Maturation Factor 1 (LMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS607Mu01 | Monoclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IP. |
| PAS607Mu01 | Polyclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS607Mu01 | CLIA Kit for Lipase Maturation Factor 1 (LMF1) | CLIA assay for Antigen Detection |
| ELS607Mu01 | ELISA Kit for Lipase Maturation Factor 1 (LMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS607Ra01 | Recombinant Lipase Maturation Factor 1 (LMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS607Ra01 | Monoclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IP. |
| PAS607Ra01 | Polyclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS607Ra01 | CLIA Kit for Lipase Maturation Factor 1 (LMF1) | CLIA assay for Antigen Detection |
| ELS607Ra01 | ELISA Kit for Lipase Maturation Factor 1 (LMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS607Ca01 | Recombinant Lipase Maturation Factor 1 (LMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS607Ca01 | Monoclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IP. |
| PAS607Ca01 | Polyclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS607Ca01 | CLIA Kit for Lipase Maturation Factor 1 (LMF1) | CLIA assay for Antigen Detection |
| ELS607Ca01 | ELISA Kit for Lipase Maturation Factor 1 (LMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS607Po01 | Recombinant Lipase Maturation Factor 1 (LMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS607Po01 | Monoclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IP. |
| PAS607Po01 | Polyclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS607Po01 | CLIA Kit for Lipase Maturation Factor 1 (LMF1) | CLIA assay for Antigen Detection |
| ELS607Po01 | ELISA Kit for Lipase Maturation Factor 1 (LMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS607Bo01 | Recombinant Lipase Maturation Factor 1 (LMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS607Bo01 | Monoclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IP. |
| PAS607Bo01 | Polyclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS607Bo01 | CLIA Kit for Lipase Maturation Factor 1 (LMF1) | CLIA assay for Antigen Detection |
| ELS607Bo01 | ELISA Kit for Lipase Maturation Factor 1 (LMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS607Rb01 | Recombinant Lipase Maturation Factor 1 (LMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS607Rb01 | Monoclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IP. |
| PAS607Rb01 | Polyclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS607Rb01 | CLIA Kit for Lipase Maturation Factor 1 (LMF1) | CLIA assay for Antigen Detection |
| ELS607Rb01 | ELISA Kit for Lipase Maturation Factor 1 (LMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS607Mo01 | Recombinant Lipase Maturation Factor 1 (LMF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS607Mo01 | Monoclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IP. |
| PAS607Mo01 | Polyclonal Antibody to Lipase Maturation Factor 1 (LMF1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS607Mo01 | CLIA Kit for Lipase Maturation Factor 1 (LMF1) | CLIA assay for Antigen Detection |
| ELS607Mo01 | ELISA Kit for Lipase Maturation Factor 1 (LMF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia."
Nat. Genet. 39:1483-1487(2007) [PubMed] [Europe PMC] [Abstract]
"Lipase maturation factor LMF1, membrane topology and interaction with lipase proteins in the endoplasmic reticulum."
J. Biol. Chem. 284:33623-33633(2009) [PubMed] [Europe PMC] [Abstract]
"Purification, cellular levels, and functional domains of lipase maturation factor 1."
Biochem. Biophys. Res. Commun. 450:423-428(2014) [PubMed] [Europe PMC] [Abstract]