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Solute Carrier Family 3, Member 2 (SLC3A2)

SLC3A2; CD98HC; 4F2; 4F2HC; 4T2HC; MDU1; NACAE; Activators Of Dibasic And Neutral Amino Acid Transport; Antigen Identified By Monoclonal Antibodies 4F2; CD98 Heavy Chain

SLC3A2 is a member of the solute carrier family and encodes a cell surface, transmembrane protein with an alpha-amylase domain. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. It associates with integrins and mediates integrin-dependent signaling related to normal cell growth and tumorigenesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. During gestation, expression in the placenta was significantly stronger at full-term than at the mid- trimester stage.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS442Hu01 Recombinant Solute Carrier Family 3, Member 2 (SLC3A2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS442Hu01 Monoclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IP.
PAS442Hu01 Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IF.
Assay Kits CLS442Hu01 CLIA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) CLIA assay for Antigen Detection
ELS442Hu01 ELISA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS442Mu01 Recombinant Solute Carrier Family 3, Member 2 (SLC3A2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS442Mu01 Monoclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IP.
PAS442Mu01 Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IF.
Assay Kits CLS442Mu01 CLIA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) CLIA assay for Antigen Detection
ELS442Mu01 ELISA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS442Ra01 Recombinant Solute Carrier Family 3, Member 2 (SLC3A2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS442Ra01 Monoclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IP.
PAS442Ra01 Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IF.
Assay Kits CLS442Ra01 CLIA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) CLIA assay for Antigen Detection
ELS442Ra01 ELISA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS442Ca01 Recombinant Solute Carrier Family 3, Member 2 (SLC3A2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS442Ca01 Monoclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IP.
PAS442Ca01 Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IF.
Assay Kits CLS442Ca01 CLIA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) CLIA assay for Antigen Detection
ELS442Ca01 ELISA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS442Po01 Recombinant Solute Carrier Family 3, Member 2 (SLC3A2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS442Po01 Monoclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IP.
PAS442Po01 Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IF.
Assay Kits CLS442Po01 CLIA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) CLIA assay for Antigen Detection
ELS442Po01 ELISA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS442Bo01 Recombinant Solute Carrier Family 3, Member 2 (SLC3A2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS442Bo01 Monoclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IP.
PAS442Bo01 Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IF.
Assay Kits CLS442Bo01 CLIA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) CLIA assay for Antigen Detection
ELS442Bo01 ELISA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS442Rb01 Recombinant Solute Carrier Family 3, Member 2 (SLC3A2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS442Rb01 Monoclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IP.
PAS442Rb01 Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IF.
Assay Kits CLS442Rb01 CLIA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) CLIA assay for Antigen Detection
ELS442Rb01 ELISA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS442Mo01 Recombinant Solute Carrier Family 3, Member 2 (SLC3A2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS442Mo01 Monoclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IP.
PAS442Mo01 Polyclonal Antibody to Solute Carrier Family 3, Member 2 (SLC3A2) WB; IHC; ICC; IF.
Assay Kits CLS442Mo01 CLIA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) CLIA assay for Antigen Detection
ELS442Mo01 ELISA Kit for Solute Carrier Family 3, Member 2 (SLC3A2) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Molecular cloning of complementary DNAs encoding the heavy chain of the human 4F2 cell-surface antigen: a type II membrane glycoprotein involved in normal and neoplastic cell growth."
Proc. Natl. Acad. Sci. U.S.A. 84:6526-6530(1987) [PubMed] [Europe PMC] [Abstract]

Erratum
Proc. Natl. Acad. Sci. U.S.A. 84:8618-8618(1987)

"Primary structure of the human 4F2 antigen heavy chain predicts a transmembrane protein with a cytoplasmic NH2 terminus."
J. Biol. Chem. 262:9574-9580(1987) [PubMed] [Europe PMC] [Abstract]

"Cloning, sequence analysis, and expression of the large subunit of the human lymphocyte activation antigen 4F2."
Proc. Natl. Acad. Sci. U.S.A. 84:9204-9208(1987) [PubMed] [Europe PMC] [Abstract]

"Isolation and structural characterization of the human 4F2 heavy-chain gene, an inducible gene involved in T-lymphocyte activation."
Mol. Cell. Biol. 8:3809-3819(1988) [PubMed] [Europe PMC] [Abstract]

"Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines."
Biochim. Biophys. Acta 1514:291-302(2001) [PubMed] [Europe PMC] [Abstract]

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]