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Sodium/Glucose Cotransporter 1 (SGLT1)

SLC5A1; NAGT; Solute Carrier Family 5 Member 1; High affinity sodium-glucose cotransporter; Na(+)/glucose cotransporter 1

Glucose transporters are integral membrane proteins that mediate the transport of glucose and structurally-related substances across cellular membranes. Two families of glucose transporter have been identified: the facilitated diffusion glucose transporter family (GLUT family), also known as 'uniporters,' and the sodium-dependent glucose transporter family (SGLT family), also known as 'cotransporters' or 'symporters'. The SLC5A1 gene encodes a protein that is involved in the active transport of glucose and galactose into eukaryotic and some prokaryotic cells.The SLC5A1 protein contains a core of 13 transmembrane domains, which it shares with other members of the gene family, and it contains an additional transmembrane appended to the C termin.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS416Hu01 Recombinant Sodium/Glucose Cotransporter 1 (SGLT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS416Hu01 Monoclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IP.
PAS416Hu01 Polyclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IF.
Assay Kits CLS416Hu01 CLIA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) CLIA assay for Antigen Detection
ELS416Hu01 ELISA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS416Mu01 Recombinant Sodium/Glucose Cotransporter 1 (SGLT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS416Mu01 Monoclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IP.
PAS416Mu01 Polyclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IF.
Assay Kits CLS416Mu01 CLIA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) CLIA assay for Antigen Detection
ELS416Mu01 ELISA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS416Ra01 Recombinant Sodium/Glucose Cotransporter 1 (SGLT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS416Ra01 Monoclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IP.
PAS416Ra01 Polyclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IF.
Assay Kits CLS416Ra01 CLIA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) CLIA assay for Antigen Detection
ELS416Ra01 ELISA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS416Ca01 Recombinant Sodium/Glucose Cotransporter 1 (SGLT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS416Ca01 Monoclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IP.
PAS416Ca01 Polyclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IF.
Assay Kits CLS416Ca01 CLIA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) CLIA assay for Antigen Detection
ELS416Ca01 ELISA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS416Po01 Recombinant Sodium/Glucose Cotransporter 1 (SGLT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS416Po01 Monoclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IP.
PAS416Po01 Polyclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IF.
Assay Kits CLS416Po01 CLIA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) CLIA assay for Antigen Detection
ELS416Po01 ELISA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS416Bo01 Recombinant Sodium/Glucose Cotransporter 1 (SGLT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS416Bo01 Monoclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IP.
PAS416Bo01 Polyclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IF.
Assay Kits CLS416Bo01 CLIA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) CLIA assay for Antigen Detection
ELS416Bo01 ELISA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS416Rb01 Recombinant Sodium/Glucose Cotransporter 1 (SGLT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS416Rb01 Monoclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IP.
PAS416Rb01 Polyclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IF.
Assay Kits CLS416Rb01 CLIA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) CLIA assay for Antigen Detection
ELS416Rb01 ELISA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS416Mo01 Recombinant Sodium/Glucose Cotransporter 1 (SGLT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS416Mo01 Monoclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IP.
PAS416Mo01 Polyclonal Antibody to Sodium/Glucose Cotransporter 1 (SGLT1) WB; IHC; ICC; IF.
Assay Kits CLS416Mo01 CLIA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) CLIA assay for Antigen Detection
ELS416Mo01 ELISA Kit for Sodium/Glucose Cotransporter 1 (SGLT1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Homology of the human intestinal Na+/glucose and Escherichia coli Na+/proline cotransporters."
Proc. Natl. Acad. Sci. U.S.A. 86:5748-5752(1989) [PubMed] [Europe PMC] [Abstract]

"Structure of the human Na+/glucose cotransporter gene SGLT1."
J. Biol. Chem. 269:15204-15209(1994) [PubMed] [Europe PMC] [Abstract]

"A genome annotation-driven approach to cloning the human ORFeome."
Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of human chromosome 22."
Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]

"Membrane topology of the human Na+/glucose cotransporter SGLT1."
J. Biol. Chem. 271:1925-1934(1996) [PubMed] [Europe PMC] [Abstract]

"Glucose/galactose malabsorption caused by a defect in the Na+/glucose cotransporter."
Nature 350:354-356(1991) [PubMed] [Europe PMC] [Abstract]

"Missense mutations in SGLT1 cause glucose-galactose malabsorption by trafficking defects."
Biochim. Biophys. Acta 1453:297-303(1999) [PubMed] [Europe PMC] [Abstract]

"A missense mutation in the Na(+)/glucose cotransporter gene SGLT1 in a patient with congenital glucose-galactose malabsorption: normal trafficking but inactivation of the mutant protein."
Biochim. Biophys. Acta 1536:141-147(2001) [PubMed] [Europe PMC] [Abstract]