Solute Carrier Family 30, Member 1 (SLC30A1)

ZNT1; ZRC1; Zinc Transporter 1

SPN	S314
HGNC	11012
MGI	1345281
PubMed	18936201
RGD	61918
UniProt	Q9Y6M5
Wiki	SLC30A1

Palmiter and Findley (1995) cloned rat Znt1. The 5-prime UTR is GC rich, and the deduced protein contains 507 amino acids. Znt1 has 6 membrane-spanning domains and intracellular N and C termini. Northern blot analysis detected low expression of 2.4- and 7.0-kb transcripts in all mouse tissues examined. Znt1 localized to the plasma membrane of transfected baby hamster kidney cells.

By EST database analysis, Seve et al. (2004) found evidence of moderate SLC30A1 expression in B cells and leukocytes, with lower expression in bone, brain, breast, cervix, colon, head, neck, kidney, lung, ovary, pancreas, parathyroid, placenta, prostate, stomach, and uterus.

Reference

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]