Regenerating Islet Derived Protein 3 Gamma (REG3g)
REG-III; PAP1B; PAPIB; UNQ429; Pancreatitis-associated protein 1B; Regenerating islet-derived protein III-gamma
REG3G encodes a deduced 175-amino acid protein, with a predicted molecular mass of 16.5 kD after cleavage of a putative 26-amino acid N-terminal signal peptide. Two REG3G splice forms, with identical coding sequences but different 5-prime UTRs, were identified. The REG3G and REG3A proteins share 85% sequence homology. Northern blot analysis and RT-PCR experiments showed that REG3G is strongly expressed in pancreas, moderately in testis, and weakly in heart, kidney, and placenta. Further RT-PCR analysis of pancreas-derived cell lines showed that REG3G expression is limited to exocrine pancreas. Using 3-dimensional protein structural modeling, they showed that although REG3G and REG1A share similar structural features, they display distinctive surface charge distributions.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS175Hu01 | Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS175Hu01 | Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IP. |
| PAS175Hu01 | Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS175Hu01 | CLIA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | CLIA assay for Antigen Detection |
| ELS175Hu01 | ELISA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS175Mu01 | Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS175Mu01 | Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IP. |
| PAS175Mu01 | Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS175Mu01 | CLIA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | CLIA assay for Antigen Detection |
| ELS175Mu01 | ELISA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS175Ra01 | Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS175Ra01 | Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IP. |
| PAS175Ra01 | Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS175Ra01 | CLIA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | CLIA assay for Antigen Detection |
| ELS175Ra01 | ELISA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS175Ca01 | Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS175Ca01 | Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IP. |
| PAS175Ca01 | Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS175Ca01 | CLIA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | CLIA assay for Antigen Detection |
| ELS175Ca01 | ELISA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS175Po01 | Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS175Po01 | Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IP. |
| PAS175Po01 | Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS175Po01 | CLIA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | CLIA assay for Antigen Detection |
| ELS175Po01 | ELISA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS175Bo01 | Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS175Bo01 | Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IP. |
| PAS175Bo01 | Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS175Bo01 | CLIA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | CLIA assay for Antigen Detection |
| ELS175Bo01 | ELISA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS175Rb01 | Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS175Rb01 | Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IP. |
| PAS175Rb01 | Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS175Rb01 | CLIA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | CLIA assay for Antigen Detection |
| ELS175Rb01 | ELISA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS175Mo01 | Recombinant Regenerating Islet Derived Protein 3 Gamma (REG3g) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS175Mo01 | Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IP. |
| PAS175Mo01 | Polyclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS175Mo01 | CLIA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | CLIA assay for Antigen Detection |
| ELS175Mo01 | ELISA Kit for Regenerating Islet Derived Protein 3 Gamma (REG3g) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III."
Gene 340:161-170(2004) [PubMed] [Europe PMC] [Abstract]
"PAP IB, a new member of the Reg gene family: cloning, expression, structural properties, and evolution by gene duplication."
Biochim. Biophys. Acta 1727:177-187(2005) [PubMed] [Europe PMC] [Abstract]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Regulation of C-type lectin antimicrobial activity by a flexible N-terminal prosegment."
J. Biol. Chem. 284:4881-4888(2009) [PubMed] [Europe PMC] [Abstract]
"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]