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Cyclin Dependent Kinase 18 (CDK18)

PCTK3; PCTAIRE; PCTAIRE3; Serine/Threonine-Protein Kinase PCTAIRE-3; Cell division protein kinase 18; PCTAIRE-motif protein kinase 3

The PCTAIRE protein kinases comprise a distinct subfamily of the CDC2-related serine/threonine-specific protein kinases. Meyerson et al. (1992) isolated a partial cDNA encoding PCTAIRE3. Like other members of the PCTAIRE subfamily, the predicted PCTAIRE3 protein contains an N-terminal extension relative to CDC2. The CDC2-related region of PCTAIRE3, excluding the N-terminal extension, shares 51%, 79%, and 80% protein sequence identity with CDC2, PCTK1, and PCTK2, respectively. Northern blot analysis revealed that PCTAIRE3 is expressed in a variety of human cell lines and tissues. Okuda et al. (1992) identified the mouse homolog of PCTK3 .By fluorescence in situ hybridization, Okuda et al. (1994) mapped the PCTK3 gene to 1q31-q32.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS149Hu01 Recombinant Cyclin Dependent Kinase 18 (CDK18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS149Hu01 Monoclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IP.
PAS149Hu01 Polyclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IF.
Assay Kits CLS149Hu01 CLIA Kit for Cyclin Dependent Kinase 18 (CDK18) CLIA assay for Antigen Detection
ELS149Hu01 ELISA Kit for Cyclin Dependent Kinase 18 (CDK18) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS149Mu01 Recombinant Cyclin Dependent Kinase 18 (CDK18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS149Mu01 Monoclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IP.
PAS149Mu01 Polyclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IF.
Assay Kits CLS149Mu01 CLIA Kit for Cyclin Dependent Kinase 18 (CDK18) CLIA assay for Antigen Detection
ELS149Mu01 ELISA Kit for Cyclin Dependent Kinase 18 (CDK18) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS149Ra01 Recombinant Cyclin Dependent Kinase 18 (CDK18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS149Ra01 Monoclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IP.
PAS149Ra01 Polyclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IF.
Assay Kits CLS149Ra01 CLIA Kit for Cyclin Dependent Kinase 18 (CDK18) CLIA assay for Antigen Detection
ELS149Ra01 ELISA Kit for Cyclin Dependent Kinase 18 (CDK18) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS149Ca01 Recombinant Cyclin Dependent Kinase 18 (CDK18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS149Ca01 Monoclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IP.
PAS149Ca01 Polyclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IF.
Assay Kits CLS149Ca01 CLIA Kit for Cyclin Dependent Kinase 18 (CDK18) CLIA assay for Antigen Detection
ELS149Ca01 ELISA Kit for Cyclin Dependent Kinase 18 (CDK18) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS149Po01 Recombinant Cyclin Dependent Kinase 18 (CDK18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS149Po01 Monoclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IP.
PAS149Po01 Polyclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IF.
Assay Kits CLS149Po01 CLIA Kit for Cyclin Dependent Kinase 18 (CDK18) CLIA assay for Antigen Detection
ELS149Po01 ELISA Kit for Cyclin Dependent Kinase 18 (CDK18) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS149Bo01 Recombinant Cyclin Dependent Kinase 18 (CDK18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS149Bo01 Monoclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IP.
PAS149Bo01 Polyclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IF.
Assay Kits CLS149Bo01 CLIA Kit for Cyclin Dependent Kinase 18 (CDK18) CLIA assay for Antigen Detection
ELS149Bo01 ELISA Kit for Cyclin Dependent Kinase 18 (CDK18) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS149Rb01 Recombinant Cyclin Dependent Kinase 18 (CDK18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS149Rb01 Monoclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IP.
PAS149Rb01 Polyclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IF.
Assay Kits CLS149Rb01 CLIA Kit for Cyclin Dependent Kinase 18 (CDK18) CLIA assay for Antigen Detection
ELS149Rb01 ELISA Kit for Cyclin Dependent Kinase 18 (CDK18) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS149Mo01 Recombinant Cyclin Dependent Kinase 18 (CDK18) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS149Mo01 Monoclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IP.
PAS149Mo01 Polyclonal Antibody to Cyclin Dependent Kinase 18 (CDK18) WB; IHC; ICC; IF.
Assay Kits CLS149Mo01 CLIA Kit for Cyclin Dependent Kinase 18 (CDK18) CLIA assay for Antigen Detection
ELS149Mo01 ELISA Kit for Cyclin Dependent Kinase 18 (CDK18) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Cloning and expression analysis of two novel PCTAIRE 3 transcripts from human brain."
Gene 328:59-67(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"A family of human cdc2-related protein kinases."
EMBO J. 11:2909-2917(1992) [PubMed] [Europe PMC] [Abstract]

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"Large-scale proteomics analysis of the human kinome."
Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"Patterns of somatic mutation in human cancer genomes."
Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]