Sphingosine Kinase 2 (SPHK2)
SPHK2 contains the 5 highly conserved regions identified in SPHK1, although the GGKGK positively charged motif of SPHK1 is modified to GGRGL in SPHK2. In addition, SPHK2 has a region homologous to the diacylglycerol kinase catalytic site. SPHK2 shares 83% identity with mouse Sphk2. Northern blot analysis revealed a 2.8-kb transcript expressed in all 12 tissues tested, with highest expression in kidney, liver, and brain. Northern blot analysis of a mouse tissue panel revealed ubiquitous expression of a 3.1-kb transcript, with highest expression in liver and heart.SPHK2 associated with HDAC1 and HDAC2 in repressor complexes and was selectively enriched at the promoters of the genes encoding the cyclin-dependent kinase inhibitor p21 or the transcriptional regulator c-fos, where it enhanced local histone H3 acetylation and transcription.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS102Hu01 | Recombinant Sphingosine Kinase 2 (SPHK2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS102Hu01 | Monoclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IP. |
| PAS102Hu01 | Polyclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS102Hu01 | CLIA Kit for Sphingosine Kinase 2 (SPHK2) | CLIA assay for Antigen Detection |
| ELS102Hu01 | ELISA Kit for Sphingosine Kinase 2 (SPHK2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS102Mu01 | Recombinant Sphingosine Kinase 2 (SPHK2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS102Mu01 | Monoclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IP. |
| PAS102Mu01 | Polyclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS102Mu01 | CLIA Kit for Sphingosine Kinase 2 (SPHK2) | CLIA assay for Antigen Detection |
| ELS102Mu01 | ELISA Kit for Sphingosine Kinase 2 (SPHK2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS102Ra01 | Recombinant Sphingosine Kinase 2 (SPHK2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS102Ra01 | Monoclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IP. |
| PAS102Ra01 | Polyclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS102Ra01 | CLIA Kit for Sphingosine Kinase 2 (SPHK2) | CLIA assay for Antigen Detection |
| ELS102Ra01 | ELISA Kit for Sphingosine Kinase 2 (SPHK2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS102Ca01 | Recombinant Sphingosine Kinase 2 (SPHK2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS102Ca01 | Monoclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IP. |
| PAS102Ca01 | Polyclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS102Ca01 | CLIA Kit for Sphingosine Kinase 2 (SPHK2) | CLIA assay for Antigen Detection |
| ELS102Ca01 | ELISA Kit for Sphingosine Kinase 2 (SPHK2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS102Po01 | Recombinant Sphingosine Kinase 2 (SPHK2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS102Po01 | Monoclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IP. |
| PAS102Po01 | Polyclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS102Po01 | CLIA Kit for Sphingosine Kinase 2 (SPHK2) | CLIA assay for Antigen Detection |
| ELS102Po01 | ELISA Kit for Sphingosine Kinase 2 (SPHK2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS102Bo01 | Recombinant Sphingosine Kinase 2 (SPHK2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS102Bo01 | Monoclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IP. |
| PAS102Bo01 | Polyclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS102Bo01 | CLIA Kit for Sphingosine Kinase 2 (SPHK2) | CLIA assay for Antigen Detection |
| ELS102Bo01 | ELISA Kit for Sphingosine Kinase 2 (SPHK2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS102Rb01 | Recombinant Sphingosine Kinase 2 (SPHK2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS102Rb01 | Monoclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IP. |
| PAS102Rb01 | Polyclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS102Rb01 | CLIA Kit for Sphingosine Kinase 2 (SPHK2) | CLIA assay for Antigen Detection |
| ELS102Rb01 | ELISA Kit for Sphingosine Kinase 2 (SPHK2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS102Mo01 | Recombinant Sphingosine Kinase 2 (SPHK2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS102Mo01 | Monoclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IP. |
| PAS102Mo01 | Polyclonal Antibody to Sphingosine Kinase 2 (SPHK2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS102Mo01 | CLIA Kit for Sphingosine Kinase 2 (SPHK2) | CLIA assay for Antigen Detection |
| ELS102Mo01 | ELISA Kit for Sphingosine Kinase 2 (SPHK2) | Enzyme-linked immunosorbent assay for Antigen Detection |
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