Inhibitory Subunit Of NF Kappa B Delta (IkBd)

NFKBID; IKBNS; TA-NFKBH; IkappaBNS; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor,Delta; T-cell activation NFKB-like protein

SPN	S100
HGNC	15671
MGI	3041243
PubMed	22908111
RGD	1308055
UniProt	Q8NI38

Inhibitory Subunit Of NF Kappa B Delta belongs to the NF-kappa-B inhibitor family.May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR- induced negative selection of thymocytes (By similarity).

Tissue expression: blood; brain; embryonic tissue; eye; heart; intestine; kidney; lung; lymph node; mammary gland; ovary; pharynx; placenta; stomach; testis; thyroid; tonsil; breast (mammary gland) tumor; colorectal tumor; gastrointestinal tumor; germ cell tumor; head and neck tumor; leukemia; lung tumor; normal; ovarian tumor; embryoid body; fetus; adult; Interacts with NFKB1, RELA and RELB; in the nucleus

Reference

"T lymphocyte activation gene identification by coregulated expression on DNA microarrays."
Genomics 83:989-999(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]