Tubulin Epsilon (TUBe)

TUBE1

SPN	S083
HGNC	20775
MGI	1919174
PubMed	10620804
RGD	1306048
UniProt	Q9UJT0
Wiki	TUBE1

TUBe encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication. A pseudogene of this gene is found on chromosome 5.
The deduced 475-amino acid protein has a calculated molecular mass of 53 kD. TUBE contains the conserved GTP-binding domain shared with other tubulins, but it lacks the highly acidic C terminus characteristic of alpha-tubulin and beta-tubulin. Relative to other tubulins, it also has a 26-amino acid insertion between helices 6 and 7.Localization of TUBE within the centrosome of dividing osteogenic sarcoma cells was dependent on the cell-cycle stage.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS083Hu01	Recombinant Tubulin Epsilon (TUBe)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS083Hu01	Monoclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IP.
Antibodies	PAS083Hu01	Polyclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IF.
Assay Kits	CLS083Hu01	CLIA Kit for Tubulin Epsilon (TUBe)	CLIA assay for Antigen Detection
Assay Kits	ELS083Hu01	ELISA Kit for Tubulin Epsilon (TUBe)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS083Mu01	Recombinant Tubulin Epsilon (TUBe)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS083Mu01	Monoclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IP.
Antibodies	PAS083Mu01	Polyclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IF.
Assay Kits	CLS083Mu01	CLIA Kit for Tubulin Epsilon (TUBe)	CLIA assay for Antigen Detection
Assay Kits	ELS083Mu01	ELISA Kit for Tubulin Epsilon (TUBe)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS083Ra01	Recombinant Tubulin Epsilon (TUBe)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS083Ra01	Monoclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IP.
Antibodies	PAS083Ra01	Polyclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IF.
Assay Kits	CLS083Ra01	CLIA Kit for Tubulin Epsilon (TUBe)	CLIA assay for Antigen Detection
Assay Kits	ELS083Ra01	ELISA Kit for Tubulin Epsilon (TUBe)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS083Ca01	Recombinant Tubulin Epsilon (TUBe)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS083Ca01	Monoclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IP.
Antibodies	PAS083Ca01	Polyclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IF.
Assay Kits	CLS083Ca01	CLIA Kit for Tubulin Epsilon (TUBe)	CLIA assay for Antigen Detection
Assay Kits	ELS083Ca01	ELISA Kit for Tubulin Epsilon (TUBe)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS083Po01	Recombinant Tubulin Epsilon (TUBe)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS083Po01	Monoclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IP.
Antibodies	PAS083Po01	Polyclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IF.
Assay Kits	CLS083Po01	CLIA Kit for Tubulin Epsilon (TUBe)	CLIA assay for Antigen Detection
Assay Kits	ELS083Po01	ELISA Kit for Tubulin Epsilon (TUBe)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS083Bo01	Recombinant Tubulin Epsilon (TUBe)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS083Bo01	Monoclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IP.
Antibodies	PAS083Bo01	Polyclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IF.
Assay Kits	CLS083Bo01	CLIA Kit for Tubulin Epsilon (TUBe)	CLIA assay for Antigen Detection
Assay Kits	ELS083Bo01	ELISA Kit for Tubulin Epsilon (TUBe)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS083Rb01	Recombinant Tubulin Epsilon (TUBe)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS083Rb01	Monoclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IP.
Antibodies	PAS083Rb01	Polyclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IF.
Assay Kits	CLS083Rb01	CLIA Kit for Tubulin Epsilon (TUBe)	CLIA assay for Antigen Detection
Assay Kits	ELS083Rb01	ELISA Kit for Tubulin Epsilon (TUBe)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS083Mo01	Recombinant Tubulin Epsilon (TUBe)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS083Mo01	Monoclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IP.
Antibodies	PAS083Mo01	Polyclonal Antibody to Tubulin Epsilon (TUBe)	WB; IHC; ICC; IF.
Assay Kits	CLS083Mo01	CLIA Kit for Tubulin Epsilon (TUBe)	CLIA assay for Antigen Detection
Assay Kits	ELS083Mo01	ELISA Kit for Tubulin Epsilon (TUBe)	Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function."
Nat. Cell Biol. 2:30-35(2000) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]