Alcohol Dehydrogenase 3 (ADH3)

ADH1C; Alcohol dehydrogenase subunit gamma

SPN	R950
HGNC	251
MGI	87921
PubMed	12710951
RGD	2044
UniProt	P00326
Wiki	ADH1C

The amino acid numbering system used throughout reflects inclusion of the ATG translation initiation codon in the ADH1C sequence. Alcohol dehydrogenase 1C is encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR950Hu01	Recombinant Alcohol Dehydrogenase 3 (ADH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR950Hu01	Monoclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IP.
Antibodies	PAR950Hu01	Polyclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IF.
Assay Kits	CLR950Hu01	CLIA Kit for Alcohol Dehydrogenase 3 (ADH3)	CLIA assay for Antigen Detection
Assay Kits	ELR950Hu01	ELISA Kit for Alcohol Dehydrogenase 3 (ADH3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR950Mu01	Recombinant Alcohol Dehydrogenase 3 (ADH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR950Mu01	Monoclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IP.
Antibodies	PAR950Mu01	Polyclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IF.
Assay Kits	CLR950Mu01	CLIA Kit for Alcohol Dehydrogenase 3 (ADH3)	CLIA assay for Antigen Detection
Assay Kits	ELR950Mu01	ELISA Kit for Alcohol Dehydrogenase 3 (ADH3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR950Ra01	Recombinant Alcohol Dehydrogenase 3 (ADH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR950Ra01	Monoclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IP.
Antibodies	PAR950Ra01	Polyclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IF.
Assay Kits	CLR950Ra01	CLIA Kit for Alcohol Dehydrogenase 3 (ADH3)	CLIA assay for Antigen Detection
Assay Kits	ELR950Ra01	ELISA Kit for Alcohol Dehydrogenase 3 (ADH3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR950Ca01	Recombinant Alcohol Dehydrogenase 3 (ADH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR950Ca01	Monoclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IP.
Antibodies	PAR950Ca01	Polyclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IF.
Assay Kits	CLR950Ca01	CLIA Kit for Alcohol Dehydrogenase 3 (ADH3)	CLIA assay for Antigen Detection
Assay Kits	ELR950Ca01	ELISA Kit for Alcohol Dehydrogenase 3 (ADH3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR950Po01	Recombinant Alcohol Dehydrogenase 3 (ADH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR950Po01	Monoclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IP.
Antibodies	PAR950Po01	Polyclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IF.
Assay Kits	CLR950Po01	CLIA Kit for Alcohol Dehydrogenase 3 (ADH3)	CLIA assay for Antigen Detection
Assay Kits	ELR950Po01	ELISA Kit for Alcohol Dehydrogenase 3 (ADH3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR950Bo01	Recombinant Alcohol Dehydrogenase 3 (ADH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR950Bo01	Monoclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IP.
Antibodies	PAR950Bo01	Polyclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IF.
Assay Kits	CLR950Bo01	CLIA Kit for Alcohol Dehydrogenase 3 (ADH3)	CLIA assay for Antigen Detection
Assay Kits	ELR950Bo01	ELISA Kit for Alcohol Dehydrogenase 3 (ADH3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR950Rb01	Recombinant Alcohol Dehydrogenase 3 (ADH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR950Rb01	Monoclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IP.
Antibodies	PAR950Rb01	Polyclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IF.
Assay Kits	CLR950Rb01	CLIA Kit for Alcohol Dehydrogenase 3 (ADH3)	CLIA assay for Antigen Detection
Assay Kits	ELR950Rb01	ELISA Kit for Alcohol Dehydrogenase 3 (ADH3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR950Mo01	Recombinant Alcohol Dehydrogenase 3 (ADH3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR950Mo01	Monoclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IP.
Antibodies	PAR950Mo01	Polyclonal Antibody to Alcohol Dehydrogenase 3 (ADH3)	WB; IHC; ICC; IF.
Assay Kits	CLR950Mo01	CLIA Kit for Alcohol Dehydrogenase 3 (ADH3)	CLIA assay for Antigen Detection
Assay Kits	ELR950Mo01	ELISA Kit for Alcohol Dehydrogenase 3 (ADH3)	Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"The gamma 1 and gamma 2 subunits of human liver alcohol dehydrogenase. cDNA structures, two amino acid replacements, and compatibility with changes in the enzymatic properties."
Eur. J. Biochem. 159:215-218(1986) [PubMed] [Europe PMC] [Abstract]

"Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence."
Proc. Natl. Acad. Sci. U.S.A. 83:634-638(1986) [PubMed] [Europe PMC] [Abstract]

"Molecular structure of the human alcohol dehydrogenase 3 gene."
Jpn. J. Genet. 67:167-171(1992) [PubMed] [Europe PMC] [Abstract]

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Human liver alcohol dehydrogenase. 2. The primary structure of the gamma 1 protein chain."
Eur. J. Biochem. 145:447-453(1984) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"Three-dimensional structures of the three human class I alcohol dehydrogenases."
Protein Sci. 10:697-706(2001) [PubMed] [Europe PMC] [Abstract]

"Structure of three class I human alcohol dehydrogenases complexed with isoenzyme specific formamide inhibitors."
Biochemistry 43:12555-12562(2004) [PubMed] [Europe PMC] [Abstract]