Complement Component 1, Q Subcomponent C (C1qC)
C1QG; Complement Component 1 q subcomponent,Gamma Polypeptide
C1qCencodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis.
C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR944Hu01 | Recombinant Complement Component 1, Q Subcomponent C (C1qC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR944Hu01 | Monoclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IP. |
| PAR944Hu01 | Polyclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR944Hu01 | CLIA Kit for Complement Component 1, Q Subcomponent C (C1qC) | CLIA assay for Antigen Detection |
| ELR944Hu01 | ELISA Kit for Complement Component 1, Q Subcomponent C (C1qC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR944Mu01 | Recombinant Complement Component 1, Q Subcomponent C (C1qC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR944Mu01 | Monoclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IP. |
| PAR944Mu01 | Polyclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR944Mu01 | CLIA Kit for Complement Component 1, Q Subcomponent C (C1qC) | CLIA assay for Antigen Detection |
| ELR944Mu01 | ELISA Kit for Complement Component 1, Q Subcomponent C (C1qC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR944Ra01 | Recombinant Complement Component 1, Q Subcomponent C (C1qC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR944Ra01 | Monoclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IP. |
| PAR944Ra01 | Polyclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR944Ra01 | CLIA Kit for Complement Component 1, Q Subcomponent C (C1qC) | CLIA assay for Antigen Detection |
| ELR944Ra01 | ELISA Kit for Complement Component 1, Q Subcomponent C (C1qC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR944Ca01 | Recombinant Complement Component 1, Q Subcomponent C (C1qC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR944Ca01 | Monoclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IP. |
| PAR944Ca01 | Polyclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR944Ca01 | CLIA Kit for Complement Component 1, Q Subcomponent C (C1qC) | CLIA assay for Antigen Detection |
| ELR944Ca01 | ELISA Kit for Complement Component 1, Q Subcomponent C (C1qC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR944Po01 | Recombinant Complement Component 1, Q Subcomponent C (C1qC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR944Po01 | Monoclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IP. |
| PAR944Po01 | Polyclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR944Po01 | CLIA Kit for Complement Component 1, Q Subcomponent C (C1qC) | CLIA assay for Antigen Detection |
| ELR944Po01 | ELISA Kit for Complement Component 1, Q Subcomponent C (C1qC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR944Bo01 | Recombinant Complement Component 1, Q Subcomponent C (C1qC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR944Bo01 | Monoclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IP. |
| PAR944Bo01 | Polyclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR944Bo01 | CLIA Kit for Complement Component 1, Q Subcomponent C (C1qC) | CLIA assay for Antigen Detection |
| ELR944Bo01 | ELISA Kit for Complement Component 1, Q Subcomponent C (C1qC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR944Rb01 | Recombinant Complement Component 1, Q Subcomponent C (C1qC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR944Rb01 | Monoclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IP. |
| PAR944Rb01 | Polyclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR944Rb01 | CLIA Kit for Complement Component 1, Q Subcomponent C (C1qC) | CLIA assay for Antigen Detection |
| ELR944Rb01 | ELISA Kit for Complement Component 1, Q Subcomponent C (C1qC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR944Mo01 | Recombinant Complement Component 1, Q Subcomponent C (C1qC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR944Mo01 | Monoclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IP. |
| PAR944Mo01 | Polyclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR944Mo01 | CLIA Kit for Complement Component 1, Q Subcomponent C (C1qC) | CLIA assay for Antigen Detection |
| ELR944Mo01 | ELISA Kit for Complement Component 1, Q Subcomponent C (C1qC) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q."
Biochem. J. 274:481-490(1991) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Complete amino acid sequences of the three collagen-like regions present in subcomponent C1q of the first component of human complement."
Biochem. J. 179:367-371(1979) [PubMed] [Europe PMC] [Abstract]
"The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties."
J. Biol. Chem. 278:46974-46982(2003) [PubMed] [Europe PMC] [Abstract]
"Molecular basis of hereditary C1q deficiency."
Immunobiology 199:286-294(1998) [PubMed] [Europe PMC] [Abstract]
"Homozygous hereditary C1q deficiency and systemic lupus erythematosus. A new family and the molecular basis of C1q deficiency in three families."
Arthritis Rheum. 39:663-670(1996) [PubMed] [Europe PMC] [Abstract]