A Kinase Anchor Protein 12 (AKAP12)

AKAP250; Gravin; A-kinase anchor protein 250 kDa; Myasthenia gravis autoantigen

SPN	R910
HGNC	370
MGI	1932576
PubMed	22811901
RGD	70988
UniProt	Q02952
Wiki	AKAP12

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family.

AKAP12 is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR910Hu01	Recombinant A Kinase Anchor Protein 12 (AKAP12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR910Hu01	Monoclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IP.
Antibodies	PAR910Hu01	Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IF.
Assay Kits	CLR910Hu01	CLIA Kit for A Kinase Anchor Protein 12 (AKAP12)	CLIA assay for Antigen Detection
Assay Kits	ELR910Hu01	ELISA Kit for A Kinase Anchor Protein 12 (AKAP12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR910Mu01	Recombinant A Kinase Anchor Protein 12 (AKAP12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR910Mu01	Monoclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IP.
Antibodies	PAR910Mu01	Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IF.
Assay Kits	CLR910Mu01	CLIA Kit for A Kinase Anchor Protein 12 (AKAP12)	CLIA assay for Antigen Detection
Assay Kits	ELR910Mu01	ELISA Kit for A Kinase Anchor Protein 12 (AKAP12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR910Ra01	Recombinant A Kinase Anchor Protein 12 (AKAP12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR910Ra01	Monoclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IP.
Antibodies	PAR910Ra01	Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IF.
Assay Kits	CLR910Ra01	CLIA Kit for A Kinase Anchor Protein 12 (AKAP12)	CLIA assay for Antigen Detection
Assay Kits	ELR910Ra01	ELISA Kit for A Kinase Anchor Protein 12 (AKAP12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR910Ca01	Recombinant A Kinase Anchor Protein 12 (AKAP12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR910Ca01	Monoclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IP.
Antibodies	PAR910Ca01	Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IF.
Assay Kits	CLR910Ca01	CLIA Kit for A Kinase Anchor Protein 12 (AKAP12)	CLIA assay for Antigen Detection
Assay Kits	ELR910Ca01	ELISA Kit for A Kinase Anchor Protein 12 (AKAP12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR910Po01	Recombinant A Kinase Anchor Protein 12 (AKAP12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR910Po01	Monoclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IP.
Antibodies	PAR910Po01	Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IF.
Assay Kits	CLR910Po01	CLIA Kit for A Kinase Anchor Protein 12 (AKAP12)	CLIA assay for Antigen Detection
Assay Kits	ELR910Po01	ELISA Kit for A Kinase Anchor Protein 12 (AKAP12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR910Bo01	Recombinant A Kinase Anchor Protein 12 (AKAP12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR910Bo01	Monoclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IP.
Antibodies	PAR910Bo01	Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IF.
Assay Kits	CLR910Bo01	CLIA Kit for A Kinase Anchor Protein 12 (AKAP12)	CLIA assay for Antigen Detection
Assay Kits	ELR910Bo01	ELISA Kit for A Kinase Anchor Protein 12 (AKAP12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR910Rb01	Recombinant A Kinase Anchor Protein 12 (AKAP12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR910Rb01	Monoclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IP.
Antibodies	PAR910Rb01	Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IF.
Assay Kits	CLR910Rb01	CLIA Kit for A Kinase Anchor Protein 12 (AKAP12)	CLIA assay for Antigen Detection
Assay Kits	ELR910Rb01	ELISA Kit for A Kinase Anchor Protein 12 (AKAP12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPR910Mo01	Recombinant A Kinase Anchor Protein 12 (AKAP12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAR910Mo01	Monoclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IP.
Antibodies	PAR910Mo01	Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)	WB; IHC; ICC; IF.
Assay Kits	CLR910Mo01	CLIA Kit for A Kinase Anchor Protein 12 (AKAP12)	CLIA assay for Antigen Detection
Assay Kits	ELR910Mo01	ELISA Kit for A Kinase Anchor Protein 12 (AKAP12)	Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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