Sirtuin 4 (SIRT4)
SIR2L4; Silent Mating Type Information Regulation 2 Homolog 4; SIR2-like protein 4; NAD-dependent protein deacetylase sirtuin-4
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR885Hu01 | Recombinant Sirtuin 4 (SIRT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR885Hu01 | Monoclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IP. |
| PAR885Hu01 | Polyclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR885Hu01 | CLIA Kit for Sirtuin 4 (SIRT4) | CLIA assay for Antigen Detection |
| ELR885Hu01 | ELISA Kit for Sirtuin 4 (SIRT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR885Mu01 | Recombinant Sirtuin 4 (SIRT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR885Mu01 | Monoclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IP. |
| PAR885Mu01 | Polyclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR885Mu01 | CLIA Kit for Sirtuin 4 (SIRT4) | CLIA assay for Antigen Detection |
| ELR885Mu01 | ELISA Kit for Sirtuin 4 (SIRT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR885Ra01 | Recombinant Sirtuin 4 (SIRT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR885Ra01 | Monoclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IP. |
| PAR885Ra01 | Polyclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR885Ra01 | CLIA Kit for Sirtuin 4 (SIRT4) | CLIA assay for Antigen Detection |
| ELR885Ra01 | ELISA Kit for Sirtuin 4 (SIRT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR885Ca01 | Recombinant Sirtuin 4 (SIRT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR885Ca01 | Monoclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IP. |
| PAR885Ca01 | Polyclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR885Ca01 | CLIA Kit for Sirtuin 4 (SIRT4) | CLIA assay for Antigen Detection |
| ELR885Ca01 | ELISA Kit for Sirtuin 4 (SIRT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR885Po01 | Recombinant Sirtuin 4 (SIRT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR885Po01 | Monoclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IP. |
| PAR885Po01 | Polyclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR885Po01 | CLIA Kit for Sirtuin 4 (SIRT4) | CLIA assay for Antigen Detection |
| ELR885Po01 | ELISA Kit for Sirtuin 4 (SIRT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR885Bo01 | Recombinant Sirtuin 4 (SIRT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR885Bo01 | Monoclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IP. |
| PAR885Bo01 | Polyclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR885Bo01 | CLIA Kit for Sirtuin 4 (SIRT4) | CLIA assay for Antigen Detection |
| ELR885Bo01 | ELISA Kit for Sirtuin 4 (SIRT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR885Rb01 | Recombinant Sirtuin 4 (SIRT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR885Rb01 | Monoclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IP. |
| PAR885Rb01 | Polyclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR885Rb01 | CLIA Kit for Sirtuin 4 (SIRT4) | CLIA assay for Antigen Detection |
| ELR885Rb01 | ELISA Kit for Sirtuin 4 (SIRT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR885Mo01 | Recombinant Sirtuin 4 (SIRT4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR885Mo01 | Monoclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IP. |
| PAR885Mo01 | Polyclonal Antibody to Sirtuin 4 (SIRT4) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR885Mo01 | CLIA Kit for Sirtuin 4 (SIRT4) | CLIA assay for Antigen Detection |
| ELR885Mo01 | ELISA Kit for Sirtuin 4 (SIRT4) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity."
Biochem. Biophys. Res. Commun. 260:273-279(1999) [PubMed] [Europe PMC] [Abstract]
"The finished DNA sequence of human chromosome 12."
Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells."
Cell 126:941-954(2006) [PubMed] [Europe PMC] [Abstract]
"Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase."
J. Biol. Chem. 282:33583-33592(2007) [PubMed] [Europe PMC] [Abstract]
"Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins."
Mol. Biol. Cell 16:4623-4635(2005) [PubMed] [Europe PMC] [Abstract]
"SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism."
Cancer Cell 23:450-463(2013) [PubMed] [Europe PMC] [Abstract]
"The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4."
Cell 153:840-854(2013) [PubMed] [Europe PMC] [Abstract]