Brain Specific Angiogenesis Inhibitor 3 (BAI3)
Brain-specific angiogenesis inhibitors are G-protein coupled receptors belonging to the class B secretin subfamily. Might be involved in angiogenesis inhibition and suppression of glioblastoma.Strongly expressed in brain. Also detected in heart. Reduced expression is observed in some glioblastoma cell lines. BAI1, a p53-target gene, encodes brain-specific angiogenesis inhibitor, a seven-span transmembrane protein and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities and may also play a role in angiogenesis. C1ql proteins are secreted signaling molecules that bind to BAI3 and act, at least in part, to regulate synapse formation and/or maintenance.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR568Hu01 | Recombinant Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR568Hu01 | Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IP. |
| PAR568Hu01 | Polyclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR568Hu01 | CLIA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | CLIA assay for Antigen Detection |
| ELR568Hu01 | ELISA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR568Mu01 | Recombinant Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR568Mu01 | Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IP. |
| PAR568Mu01 | Polyclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR568Mu01 | CLIA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | CLIA assay for Antigen Detection |
| ELR568Mu01 | ELISA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR568Ra01 | Recombinant Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR568Ra01 | Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IP. |
| PAR568Ra01 | Polyclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR568Ra01 | CLIA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | CLIA assay for Antigen Detection |
| ELR568Ra01 | ELISA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR568Ca01 | Recombinant Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR568Ca01 | Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IP. |
| PAR568Ca01 | Polyclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR568Ca01 | CLIA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | CLIA assay for Antigen Detection |
| ELR568Ca01 | ELISA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR568Po01 | Recombinant Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR568Po01 | Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IP. |
| PAR568Po01 | Polyclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR568Po01 | CLIA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | CLIA assay for Antigen Detection |
| ELR568Po01 | ELISA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR568Bo01 | Recombinant Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR568Bo01 | Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IP. |
| PAR568Bo01 | Polyclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR568Bo01 | CLIA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | CLIA assay for Antigen Detection |
| ELR568Bo01 | ELISA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR568Rb01 | Recombinant Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR568Rb01 | Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IP. |
| PAR568Rb01 | Polyclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR568Rb01 | CLIA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | CLIA assay for Antigen Detection |
| ELR568Rb01 | ELISA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPR568Mo01 | Recombinant Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAR568Mo01 | Monoclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IP. |
| PAR568Mo01 | Polyclonal Antibody to Brain Specific Angiogenesis Inhibitor 3 (BAI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLR568Mo01 | CLIA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | CLIA assay for Antigen Detection |
| ELR568Mo01 | ELISA Kit for Brain Specific Angiogenesis Inhibitor 3 (BAI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1)."
Cytogenet. Cell Genet. 79:103-108(1997) [PubMed] [Europe PMC] [Abstract]
"Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
DNA Res. 5:31-39(1998) [PubMed] [Europe PMC] [Abstract]
"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
"The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins."
Proc. Natl. Acad. Sci. U.S.A. 108:2534-2539(2011) [PubMed] [Europe PMC] [Abstract]
"A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis."
EMBO J. 31:1364-1378(2012) [PubMed] [Europe PMC] [Abstract]