Hippocalcin Like Protein 4 (HPCAL4)

HLP4

SPN	R316
HGNC	18212
MGI	2157521
PubMed	19689454
RGD	708491
UniProt	Q9UM19
Wiki	HPCAL4

Hippocalcin like 4 is highly similar to human hippocalcin protein and hippocalcin like-1 protein. It also has similarity to rat neural visinin-like Ca2+-binding protein-type 1 and 2 proteins. This encoded protein may be involved in the calcium-dependent regulation of rhodopsin phosphorylation. The transcript of this gene has multiple polyadenylation sites.

Hippocalcin (HPCA) is a calcium-binding protein that belongs to neuronal calcium sensor (NCS) family of proteins. It expressed in mammalian brains especially in the hippocampus. It possesses a Ca²⁺/myristoyl switch.Hippocalcin is a member of a family of neuron-specific Ca(2+)-binding proteins found in the retina and brain.

Reference

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DNA Seq. 9:171-176(1998) [PubMed] [Europe PMC] [Abstract]

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Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]