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Taste Receptor Type 2 Member 38 (TAS2R38)

PTC; T2R61; Phenylthiocarbamide Tasting; PTC bitter taste receptor

TAS2R38 encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant).

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ996Hu01 Recombinant Taste Receptor Type 2 Member 38 (TAS2R38) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ996Hu01 Monoclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IP.
PAQ996Hu01 Polyclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IF.
Assay Kits CLQ996Hu01 CLIA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) CLIA assay for Antigen Detection
ELQ996Hu01 ELISA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ996Mu01 Recombinant Taste Receptor Type 2 Member 38 (TAS2R38) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ996Mu01 Monoclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IP.
PAQ996Mu01 Polyclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IF.
Assay Kits CLQ996Mu01 CLIA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) CLIA assay for Antigen Detection
ELQ996Mu01 ELISA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ996Ra01 Recombinant Taste Receptor Type 2 Member 38 (TAS2R38) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ996Ra01 Monoclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IP.
PAQ996Ra01 Polyclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IF.
Assay Kits CLQ996Ra01 CLIA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) CLIA assay for Antigen Detection
ELQ996Ra01 ELISA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ996Ca01 Recombinant Taste Receptor Type 2 Member 38 (TAS2R38) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ996Ca01 Monoclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IP.
PAQ996Ca01 Polyclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IF.
Assay Kits CLQ996Ca01 CLIA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) CLIA assay for Antigen Detection
ELQ996Ca01 ELISA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ996Po01 Recombinant Taste Receptor Type 2 Member 38 (TAS2R38) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ996Po01 Monoclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IP.
PAQ996Po01 Polyclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IF.
Assay Kits CLQ996Po01 CLIA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) CLIA assay for Antigen Detection
ELQ996Po01 ELISA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ996Bo01 Recombinant Taste Receptor Type 2 Member 38 (TAS2R38) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ996Bo01 Monoclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IP.
PAQ996Bo01 Polyclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IF.
Assay Kits CLQ996Bo01 CLIA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) CLIA assay for Antigen Detection
ELQ996Bo01 ELISA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ996Rb01 Recombinant Taste Receptor Type 2 Member 38 (TAS2R38) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ996Rb01 Monoclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IP.
PAQ996Rb01 Polyclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IF.
Assay Kits CLQ996Rb01 CLIA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) CLIA assay for Antigen Detection
ELQ996Rb01 ELISA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ996Mo01 Recombinant Taste Receptor Type 2 Member 38 (TAS2R38) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ996Mo01 Monoclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IP.
PAQ996Mo01 Polyclonal Antibody to Taste Receptor Type 2 Member 38 (TAS2R38) WB; IHC; ICC; IF.
Assay Kits CLQ996Mo01 CLIA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) CLIA assay for Antigen Detection
ELQ996Mo01 ELISA Kit for Taste Receptor Type 2 Member 38 (TAS2R38) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides."
Nat. Genet. 32:397-401(2002) [PubMed] [Europe PMC] [Abstract]

"Identification and characterization of human taste receptor genes belonging to the TAS2R family."
Cytogenet. Genome Res. 98:45-53(2002) [PubMed] [Europe PMC] [Abstract]

"Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide."
Science 299:1221-1225(2003) [PubMed] [Europe PMC] [Abstract]

"Evolution of bitter taste receptors in humans and apes."
Mol. Biol. Evol. 22:432-436(2005) [PubMed] [Europe PMC] [Abstract]

"Human chromosome 7: DNA sequence and biology."
Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Receptors for bitter and sweet taste."
Curr. Opin. Neurobiol. 12:366-371(2002) [PubMed] [Europe PMC] [Abstract]

"Molecular mechanisms of bitter and sweet taste transduction."
J. Biol. Chem. 277:1-4(2002) [PubMed] [Europe PMC] [Abstract]

"Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways."
Cell 112:293-301(2003) [PubMed] [Europe PMC] [Abstract]