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Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2)

VRL; OTRPC2; VRL1; Osm-9-like TRP channel 2; Vanilloid receptor-like protein 1

TRPV2encodes an ion channel that is activated by high temperatures above 52 °C. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat.TRPV2 is activated by high temperatures above 52 °C. Alternatively it can be activated at lower temperatures by chemicals, such as the research tool 2-APB, the plant cannabinoid cannabidiol, and probenecid. It is blocked by ruthenium red and lanthanum.
TRPV2 was independently discovered by two research groups and described in 1999. It was identified in the lab of David Julius as a close homolog of TRPV1, the first identified thermosensitive ion channel.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ966Hu01 Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ966Hu01 Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IP.
PAQ966Hu01 Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IF.
Assay Kits CLQ966Hu01 CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) CLIA assay for Antigen Detection
ELQ966Hu01 ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ966Mu01 Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ966Mu01 Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IP.
PAQ966Mu01 Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IF.
Assay Kits CLQ966Mu01 CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) CLIA assay for Antigen Detection
ELQ966Mu01 ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ966Ra01 Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ966Ra01 Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IP.
PAQ966Ra01 Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IF.
Assay Kits CLQ966Ra01 CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) CLIA assay for Antigen Detection
ELQ966Ra01 ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ966Ca01 Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ966Ca01 Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IP.
PAQ966Ca01 Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IF.
Assay Kits CLQ966Ca01 CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) CLIA assay for Antigen Detection
ELQ966Ca01 ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ966Po01 Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ966Po01 Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IP.
PAQ966Po01 Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IF.
Assay Kits CLQ966Po01 CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) CLIA assay for Antigen Detection
ELQ966Po01 ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ966Bo01 Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ966Bo01 Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IP.
PAQ966Bo01 Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IF.
Assay Kits CLQ966Bo01 CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) CLIA assay for Antigen Detection
ELQ966Bo01 ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ966Rb01 Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ966Rb01 Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IP.
PAQ966Rb01 Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IF.
Assay Kits CLQ966Rb01 CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) CLIA assay for Antigen Detection
ELQ966Rb01 ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ966Mo01 Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ966Mo01 Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IP.
PAQ966Mo01 Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) WB; IHC; ICC; IF.
Assay Kits CLQ966Mo01 CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) CLIA assay for Antigen Detection
ELQ966Mo01 ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"A capsaicin-receptor homologue with a high threshold for noxious heat."
Nature 398:436-441(1999) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."
J. Proteome Res. 5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of the human TRPV2 channel ankyrin repeat domain."
Protein Sci. 15:2201-2206(2006) [PubMed] [Europe PMC] [Abstract]