Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6)
CAT1; CATL; ABP/ZF; ECAC2; ZFAB; Epithelial Calcium Channel 2; CaT-like; Calcium transport protein 1
TRPV6 is a member of the Transient receptor potential (TRP) family of membrane proteins. Unlike most TRP channels, TRPV6 is selective for Ca2+ ions, similarly to its close homologue, TRPV5, which is mainly expressed in the kidney, and plays a role in Ca2+ reabsorption.Expression of TRPV6 appears to be vitamin D dependent as it is greatly reduced in animals that do not express the vitamin D receptor. Importantly, vitamin D treatment of colon cancer cells, Caco-2, also increases expression of TRPV6 gene. Vitamin D treatment of these cells also increases transport of calcium, probably via increasing TRPV6 expression.The TRPV6 calcium transporter also found in the human placenta, pancreas and prostate gland and in some species in the kidney where the related channel TRPV5 is strongly expressed.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ962Hu01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ962Hu01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IP. |
| PAQ962Hu01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ962Hu01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | CLIA assay for Antigen Detection |
| ELQ962Hu01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ962Mu01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ962Mu01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IP. |
| PAQ962Mu01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ962Mu01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | CLIA assay for Antigen Detection |
| ELQ962Mu01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ962Ra01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ962Ra01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IP. |
| PAQ962Ra01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ962Ra01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | CLIA assay for Antigen Detection |
| ELQ962Ra01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ962Ca01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ962Ca01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IP. |
| PAQ962Ca01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ962Ca01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | CLIA assay for Antigen Detection |
| ELQ962Ca01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ962Po01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ962Po01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IP. |
| PAQ962Po01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ962Po01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | CLIA assay for Antigen Detection |
| ELQ962Po01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ962Bo01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ962Bo01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IP. |
| PAQ962Bo01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ962Bo01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | CLIA assay for Antigen Detection |
| ELQ962Bo01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ962Rb01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ962Rb01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IP. |
| PAQ962Rb01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ962Rb01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | CLIA assay for Antigen Detection |
| ELQ962Rb01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ962Mo01 | Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ962Mo01 | Monoclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IP. |
| PAQ962Mo01 | Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ962Mo01 | CLIA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | CLIA assay for Antigen Detection |
| ELQ962Mo01 | ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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"The in vivo TRPV6 protein starts at a non-AUG triplet, decoded as methionine, upstream of canonical initiation at AUG."
J. Biol. Chem. 288:16629-16644(2013) [PubMed] [Europe PMC] [Abstract]
"TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity."
J. Cell Biol. 208:89-107(2015) [PubMed] [Europe PMC] [Abstract]