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Septin 3 (SEPT3)

SEP3; Neuronal-specific septin-3

Neuronal-specific septin-3 belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in multiple transcript variants.
SEP3 shares almost 100% sequence identity with mouse neuronal-specific septin-3 and rat brain-specific G-septin. Alternative splicing leads to 3 SEP3 isoforms, SEP3A, SEP3B, and SEP3C, which encode proteins of 345, 337, and 71 amino acids, respectively. SEP3A and SEP3B contain a set of consensus sequence motifs for GTP binding, 2 predicted phosphorylation sites for PKG, and a conserved binding motif for SH3 domain-containing proteins.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ943Hu01 Recombinant Septin 3 (SEPT3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ943Hu01 Monoclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IP.
PAQ943Hu01 Polyclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IF.
Assay Kits CLQ943Hu01 CLIA Kit for Septin 3 (SEPT3) CLIA assay for Antigen Detection
ELQ943Hu01 ELISA Kit for Septin 3 (SEPT3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ943Mu01 Recombinant Septin 3 (SEPT3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ943Mu01 Monoclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IP.
PAQ943Mu01 Polyclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IF.
Assay Kits CLQ943Mu01 CLIA Kit for Septin 3 (SEPT3) CLIA assay for Antigen Detection
ELQ943Mu01 ELISA Kit for Septin 3 (SEPT3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ943Ra01 Recombinant Septin 3 (SEPT3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ943Ra01 Monoclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IP.
PAQ943Ra01 Polyclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IF.
Assay Kits CLQ943Ra01 CLIA Kit for Septin 3 (SEPT3) CLIA assay for Antigen Detection
ELQ943Ra01 ELISA Kit for Septin 3 (SEPT3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ943Ca01 Recombinant Septin 3 (SEPT3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ943Ca01 Monoclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IP.
PAQ943Ca01 Polyclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IF.
Assay Kits CLQ943Ca01 CLIA Kit for Septin 3 (SEPT3) CLIA assay for Antigen Detection
ELQ943Ca01 ELISA Kit for Septin 3 (SEPT3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ943Po01 Recombinant Septin 3 (SEPT3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ943Po01 Monoclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IP.
PAQ943Po01 Polyclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IF.
Assay Kits CLQ943Po01 CLIA Kit for Septin 3 (SEPT3) CLIA assay for Antigen Detection
ELQ943Po01 ELISA Kit for Septin 3 (SEPT3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ943Bo01 Recombinant Septin 3 (SEPT3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ943Bo01 Monoclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IP.
PAQ943Bo01 Polyclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IF.
Assay Kits CLQ943Bo01 CLIA Kit for Septin 3 (SEPT3) CLIA assay for Antigen Detection
ELQ943Bo01 ELISA Kit for Septin 3 (SEPT3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ943Rb01 Recombinant Septin 3 (SEPT3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ943Rb01 Monoclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IP.
PAQ943Rb01 Polyclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IF.
Assay Kits CLQ943Rb01 CLIA Kit for Septin 3 (SEPT3) CLIA assay for Antigen Detection
ELQ943Rb01 ELISA Kit for Septin 3 (SEPT3) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ943Mo01 Recombinant Septin 3 (SEPT3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ943Mo01 Monoclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IP.
PAQ943Mo01 Polyclonal Antibody to Septin 3 (SEPT3) WB; IHC; ICC; IF.
Assay Kits CLQ943Mo01 CLIA Kit for Septin 3 (SEPT3) CLIA assay for Antigen Detection
ELQ943Mo01 ELISA Kit for Septin 3 (SEPT3) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Human septin 3 on chromosome 22q13.2 is upregulated by neuronal differentiation."
Biochem. Biophys. Res. Commun. 283:48-56(2001) [PubMed] [Europe PMC] [Abstract]

"A genome annotation-driven approach to cloning the human ORFeome."
Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]

"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of human chromosome 22."
Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Expression profiling the human septin gene family."
J. Pathol. 206:269-278(2005) [PubMed] [Europe PMC] [Abstract]

"The structure and properties of septin 3: a possible missing link in septin filament formation."
Biochem. J. 450:95-105(2013) [PubMed] [Europe PMC] [Abstract]