Sestrin 3 (SESN3)

SEST3

SPN	Q930
HGNC	23060
MGI	1922997
PubMed	8889548
RGD	1309470
UniProt	P58005
Wiki	SEPT3

By database mining, Peeters et al. (2003) identified a gene family related to p53-activated gene-26 (PA26), which they termed the sestrin family. Sequence alignment of human and mouse sestrin protein family members showed that the gene family is highly conserved. The SEST3 gene encodes a deduced 492-amino acid protein.

Using FISH, Peeters et al. (2003) confirmed the localization of the human sestrin genes PA26, SEST2 , and SEST3 to chromosomes 6q21, 1p35.3, and 11q21, respectively. Using the same method, they mapped the mouse Pa26, Sest2, and Sest3 genes to syntenic regions on chromosomes 4, 9, and 10, respectively.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ930Hu01	Recombinant Sestrin 3 (SESN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ930Hu01	Monoclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IP.
Antibodies	PAQ930Hu01	Polyclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IF.
Assay Kits	CLQ930Hu01	CLIA Kit for Sestrin 3 (SESN3)	CLIA assay for Antigen Detection
Assay Kits	ELQ930Hu01	ELISA Kit for Sestrin 3 (SESN3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ930Mu01	Recombinant Sestrin 3 (SESN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ930Mu01	Monoclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IP.
Antibodies	PAQ930Mu01	Polyclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IF.
Assay Kits	CLQ930Mu01	CLIA Kit for Sestrin 3 (SESN3)	CLIA assay for Antigen Detection
Assay Kits	ELQ930Mu01	ELISA Kit for Sestrin 3 (SESN3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ930Ra01	Recombinant Sestrin 3 (SESN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ930Ra01	Monoclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IP.
Antibodies	PAQ930Ra01	Polyclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IF.
Assay Kits	CLQ930Ra01	CLIA Kit for Sestrin 3 (SESN3)	CLIA assay for Antigen Detection
Assay Kits	ELQ930Ra01	ELISA Kit for Sestrin 3 (SESN3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ930Ca01	Recombinant Sestrin 3 (SESN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ930Ca01	Monoclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IP.
Antibodies	PAQ930Ca01	Polyclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IF.
Assay Kits	CLQ930Ca01	CLIA Kit for Sestrin 3 (SESN3)	CLIA assay for Antigen Detection
Assay Kits	ELQ930Ca01	ELISA Kit for Sestrin 3 (SESN3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ930Po01	Recombinant Sestrin 3 (SESN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ930Po01	Monoclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IP.
Antibodies	PAQ930Po01	Polyclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IF.
Assay Kits	CLQ930Po01	CLIA Kit for Sestrin 3 (SESN3)	CLIA assay for Antigen Detection
Assay Kits	ELQ930Po01	ELISA Kit for Sestrin 3 (SESN3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ930Bo01	Recombinant Sestrin 3 (SESN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ930Bo01	Monoclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IP.
Antibodies	PAQ930Bo01	Polyclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IF.
Assay Kits	CLQ930Bo01	CLIA Kit for Sestrin 3 (SESN3)	CLIA assay for Antigen Detection
Assay Kits	ELQ930Bo01	ELISA Kit for Sestrin 3 (SESN3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ930Rb01	Recombinant Sestrin 3 (SESN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ930Rb01	Monoclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IP.
Antibodies	PAQ930Rb01	Polyclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IF.
Assay Kits	CLQ930Rb01	CLIA Kit for Sestrin 3 (SESN3)	CLIA assay for Antigen Detection
Assay Kits	ELQ930Rb01	ELISA Kit for Sestrin 3 (SESN3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ930Mo01	Recombinant Sestrin 3 (SESN3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ930Mo01	Monoclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IP.
Antibodies	PAQ930Mo01	Polyclonal Antibody to Sestrin 3 (SESN3)	WB; IHC; ICC; IF.
Assay Kits	CLQ930Mo01	CLIA Kit for Sestrin 3 (SESN3)	CLIA assay for Antigen Detection
Assay Kits	ELQ930Mo01	ELISA Kit for Sestrin 3 (SESN3)	Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"PA26 is a candidate gene for heterotaxia in humans: identification of a novel PA26-related gene family in human and mouse."
Hum. Genet. 112:573-580(2003) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]