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Adenosine A1 Receptor (ADORA1)

RDC7

The receptor is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene.
Activation of the adenosine A1 receptor by an agonist causes binding of Gi1/2/3 or Go protein. Binding of Gi1/2/3 causes an inhibition of adenylate cyclase and therefore a decrease in the cAMP concentration.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ797Hu01 Recombinant Adenosine A1 Receptor (ADORA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ797Hu01 Monoclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IP.
PAQ797Hu01 Polyclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IF.
Assay Kits CLQ797Hu01 CLIA Kit for Adenosine A1 Receptor (ADORA1) CLIA assay for Antigen Detection
ELQ797Hu01 ELISA Kit for Adenosine A1 Receptor (ADORA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ797Mu01 Recombinant Adenosine A1 Receptor (ADORA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ797Mu01 Monoclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IP.
PAQ797Mu01 Polyclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IF.
Assay Kits CLQ797Mu01 CLIA Kit for Adenosine A1 Receptor (ADORA1) CLIA assay for Antigen Detection
ELQ797Mu01 ELISA Kit for Adenosine A1 Receptor (ADORA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ797Ra01 Recombinant Adenosine A1 Receptor (ADORA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ797Ra01 Monoclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IP.
PAQ797Ra01 Polyclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IF.
Assay Kits CLQ797Ra01 CLIA Kit for Adenosine A1 Receptor (ADORA1) CLIA assay for Antigen Detection
ELQ797Ra01 ELISA Kit for Adenosine A1 Receptor (ADORA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ797Ca01 Recombinant Adenosine A1 Receptor (ADORA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ797Ca01 Monoclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IP.
PAQ797Ca01 Polyclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IF.
Assay Kits CLQ797Ca01 CLIA Kit for Adenosine A1 Receptor (ADORA1) CLIA assay for Antigen Detection
ELQ797Ca01 ELISA Kit for Adenosine A1 Receptor (ADORA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ797Po01 Recombinant Adenosine A1 Receptor (ADORA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ797Po01 Monoclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IP.
PAQ797Po01 Polyclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IF.
Assay Kits CLQ797Po01 CLIA Kit for Adenosine A1 Receptor (ADORA1) CLIA assay for Antigen Detection
ELQ797Po01 ELISA Kit for Adenosine A1 Receptor (ADORA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ797Bo01 Recombinant Adenosine A1 Receptor (ADORA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ797Bo01 Monoclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IP.
PAQ797Bo01 Polyclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IF.
Assay Kits CLQ797Bo01 CLIA Kit for Adenosine A1 Receptor (ADORA1) CLIA assay for Antigen Detection
ELQ797Bo01 ELISA Kit for Adenosine A1 Receptor (ADORA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ797Rb01 Recombinant Adenosine A1 Receptor (ADORA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ797Rb01 Monoclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IP.
PAQ797Rb01 Polyclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IF.
Assay Kits CLQ797Rb01 CLIA Kit for Adenosine A1 Receptor (ADORA1) CLIA assay for Antigen Detection
ELQ797Rb01 ELISA Kit for Adenosine A1 Receptor (ADORA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ797Mo01 Recombinant Adenosine A1 Receptor (ADORA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ797Mo01 Monoclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IP.
PAQ797Mo01 Polyclonal Antibody to Adenosine A1 Receptor (ADORA1) WB; IHC; ICC; IF.
Assay Kits CLQ797Mo01 CLIA Kit for Adenosine A1 Receptor (ADORA1) CLIA assay for Antigen Detection
ELQ797Mo01 ELISA Kit for Adenosine A1 Receptor (ADORA1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Cloning and functional characterization of a human A1 adenosine receptor."
Biochem. Biophys. Res. Commun. 187:919-926(1992) [PubMed] [Europe PMC] [Abstract]

"Molecular cloning and characterisation of a human brain A1 adenosine receptor cDNA."
Brain Res. Mol. Brain Res. 16:365-370(1992) [PubMed] [Europe PMC] [Abstract]

"Characterization of the human A1 adenosine receptor gene. Evidence for alternative splicing."
J. Biol. Chem. 269:3104-3110(1994) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]