Proteasome Activator Subunit 3 (PSME3)

Ki; PA28G; REG-GAMMA; 11S regulator complex subunit gamma; Activator of multicatalytic protease subunit 3; Ki nuclear autoantigen; Proteasome activator 28 subunit gamma

SPN	Q531
HGNC	9570
MGI	1096366
PubMed	16893879
RGD	1306996
UniProt	P61289
Wiki	PSME3

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. PSME3 encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two transcript variants encoding different isoforms have been identified.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ531Hu01	Recombinant Proteasome Activator Subunit 3 (PSME3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ531Hu01	Monoclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IP.
Antibodies	PAQ531Hu01	Polyclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IF.
Assay Kits	CLQ531Hu01	CLIA Kit for Proteasome Activator Subunit 3 (PSME3)	CLIA assay for Antigen Detection
Assay Kits	ELQ531Hu01	ELISA Kit for Proteasome Activator Subunit 3 (PSME3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ531Mu01	Recombinant Proteasome Activator Subunit 3 (PSME3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ531Mu01	Monoclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IP.
Antibodies	PAQ531Mu01	Polyclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IF.
Assay Kits	CLQ531Mu01	CLIA Kit for Proteasome Activator Subunit 3 (PSME3)	CLIA assay for Antigen Detection
Assay Kits	ELQ531Mu01	ELISA Kit for Proteasome Activator Subunit 3 (PSME3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ531Ra01	Recombinant Proteasome Activator Subunit 3 (PSME3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ531Ra01	Monoclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IP.
Antibodies	PAQ531Ra01	Polyclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IF.
Assay Kits	CLQ531Ra01	CLIA Kit for Proteasome Activator Subunit 3 (PSME3)	CLIA assay for Antigen Detection
Assay Kits	ELQ531Ra01	ELISA Kit for Proteasome Activator Subunit 3 (PSME3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ531Ca01	Recombinant Proteasome Activator Subunit 3 (PSME3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ531Ca01	Monoclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IP.
Antibodies	PAQ531Ca01	Polyclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IF.
Assay Kits	CLQ531Ca01	CLIA Kit for Proteasome Activator Subunit 3 (PSME3)	CLIA assay for Antigen Detection
Assay Kits	ELQ531Ca01	ELISA Kit for Proteasome Activator Subunit 3 (PSME3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ531Po01	Recombinant Proteasome Activator Subunit 3 (PSME3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ531Po01	Monoclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IP.
Antibodies	PAQ531Po01	Polyclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IF.
Assay Kits	CLQ531Po01	CLIA Kit for Proteasome Activator Subunit 3 (PSME3)	CLIA assay for Antigen Detection
Assay Kits	ELQ531Po01	ELISA Kit for Proteasome Activator Subunit 3 (PSME3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ531Bo01	Recombinant Proteasome Activator Subunit 3 (PSME3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ531Bo01	Monoclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IP.
Antibodies	PAQ531Bo01	Polyclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IF.
Assay Kits	CLQ531Bo01	CLIA Kit for Proteasome Activator Subunit 3 (PSME3)	CLIA assay for Antigen Detection
Assay Kits	ELQ531Bo01	ELISA Kit for Proteasome Activator Subunit 3 (PSME3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ531Rb01	Recombinant Proteasome Activator Subunit 3 (PSME3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ531Rb01	Monoclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IP.
Antibodies	PAQ531Rb01	Polyclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IF.
Assay Kits	CLQ531Rb01	CLIA Kit for Proteasome Activator Subunit 3 (PSME3)	CLIA assay for Antigen Detection
Assay Kits	ELQ531Rb01	ELISA Kit for Proteasome Activator Subunit 3 (PSME3)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPQ531Mo01	Recombinant Proteasome Activator Subunit 3 (PSME3)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAQ531Mo01	Monoclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IP.
Antibodies	PAQ531Mo01	Polyclonal Antibody to Proteasome Activator Subunit 3 (PSME3)	WB; IHC; ICC; IF.
Assay Kits	CLQ531Mo01	CLIA Kit for Proteasome Activator Subunit 3 (PSME3)	CLIA assay for Antigen Detection
Assay Kits	ELQ531Mo01	ELISA Kit for Proteasome Activator Subunit 3 (PSME3)	Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

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Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]