Dipeptidyl Peptidase 8 (DPP8)
DP8; DPRP1; MSTP141; MSTP097; MSTP135; dipeptidylpeptidase 8; Dipeptidyl Peptidase IV-Related Protein-1; Prolyl Dipeptidase DPP VIII
Dipeptidyl peptidase 8 is member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond.
The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described.The deduced 882-amino acid DPP8 protein shares about 27% sequence identity with DPP4 and FAP; unlike these proteins, however, DPP8 has no transmembrane domain and no N- or O-linked glycosylation sites.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ367Hu01 | Recombinant Dipeptidyl Peptidase 8 (DPP8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ367Hu01 | Monoclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IP. |
| PAQ367Hu01 | Polyclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ367Hu01 | CLIA Kit for Dipeptidyl Peptidase 8 (DPP8) | CLIA assay for Antigen Detection |
| ELQ367Hu01 | ELISA Kit for Dipeptidyl Peptidase 8 (DPP8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ367Mu01 | Recombinant Dipeptidyl Peptidase 8 (DPP8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ367Mu01 | Monoclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IP. |
| PAQ367Mu01 | Polyclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ367Mu01 | CLIA Kit for Dipeptidyl Peptidase 8 (DPP8) | CLIA assay for Antigen Detection |
| ELQ367Mu01 | ELISA Kit for Dipeptidyl Peptidase 8 (DPP8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ367Ra01 | Recombinant Dipeptidyl Peptidase 8 (DPP8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ367Ra01 | Monoclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IP. |
| PAQ367Ra01 | Polyclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ367Ra01 | CLIA Kit for Dipeptidyl Peptidase 8 (DPP8) | CLIA assay for Antigen Detection |
| ELQ367Ra01 | ELISA Kit for Dipeptidyl Peptidase 8 (DPP8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ367Ca01 | Recombinant Dipeptidyl Peptidase 8 (DPP8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ367Ca01 | Monoclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IP. |
| PAQ367Ca01 | Polyclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ367Ca01 | CLIA Kit for Dipeptidyl Peptidase 8 (DPP8) | CLIA assay for Antigen Detection |
| ELQ367Ca01 | ELISA Kit for Dipeptidyl Peptidase 8 (DPP8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ367Po01 | Recombinant Dipeptidyl Peptidase 8 (DPP8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ367Po01 | Monoclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IP. |
| PAQ367Po01 | Polyclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ367Po01 | CLIA Kit for Dipeptidyl Peptidase 8 (DPP8) | CLIA assay for Antigen Detection |
| ELQ367Po01 | ELISA Kit for Dipeptidyl Peptidase 8 (DPP8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ367Bo01 | Recombinant Dipeptidyl Peptidase 8 (DPP8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ367Bo01 | Monoclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IP. |
| PAQ367Bo01 | Polyclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ367Bo01 | CLIA Kit for Dipeptidyl Peptidase 8 (DPP8) | CLIA assay for Antigen Detection |
| ELQ367Bo01 | ELISA Kit for Dipeptidyl Peptidase 8 (DPP8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ367Rb01 | Recombinant Dipeptidyl Peptidase 8 (DPP8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ367Rb01 | Monoclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IP. |
| PAQ367Rb01 | Polyclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ367Rb01 | CLIA Kit for Dipeptidyl Peptidase 8 (DPP8) | CLIA assay for Antigen Detection |
| ELQ367Rb01 | ELISA Kit for Dipeptidyl Peptidase 8 (DPP8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ367Mo01 | Recombinant Dipeptidyl Peptidase 8 (DPP8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ367Mo01 | Monoclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IP. |
| PAQ367Mo01 | Polyclonal Antibody to Dipeptidyl Peptidase 8 (DPP8) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ367Mo01 | CLIA Kit for Dipeptidyl Peptidase 8 (DPP8) | CLIA assay for Antigen Detection |
| ELQ367Mo01 | ELISA Kit for Dipeptidyl Peptidase 8 (DPP8) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8."
Eur. J. Biochem. 267:6140-6150(2000) [PubMed] [Europe PMC] [Abstract]
"Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases."
Biochem. J. 373:179-189(2003) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Structural requirements for catalysis, expression, and dimerization in the CD26/DPIV gene family."
Biochemistry 42:694-701(2003) [PubMed] [Europe PMC] [Abstract]
"Purification and characterization of human prolyl dipeptidase DPP8 in Sf9 insect cells."
Protein Expr. Purif. 35:142-146(2004) [PubMed] [Europe PMC] [Abstract]
"Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8."
Bioorg. Med. Chem. Lett. 15:687-691(2005) [PubMed] [Europe PMC] [Abstract]