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Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1)

NTRKR1; Tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase, receptor-related 1

Receptor Tyrosine Kinase Like Orphan Receptor 1 is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. Alternative splicing results in multiple transcript variants encoding different isoforms.
NTRKR1 encodes a predicted 937-amino acid protein. By Northern blot analysis, Reddy et al. (1996) showed that a 6-kb NTRKR1 mRNA is expressed strongly in human heart, lung, and kidney, but weakly in the CNS. However, a truncated 2.4-kb mRNA lacking extracellular and transmembrane domains was strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ283Hu01 Recombinant Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ283Hu01 Monoclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IP.
PAQ283Hu01 Polyclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IF.
Assay Kits CLQ283Hu01 CLIA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) CLIA assay for Antigen Detection
ELQ283Hu01 ELISA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ283Mu01 Recombinant Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ283Mu01 Monoclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IP.
PAQ283Mu01 Polyclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IF.
Assay Kits CLQ283Mu01 CLIA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) CLIA assay for Antigen Detection
ELQ283Mu01 ELISA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ283Ra01 Recombinant Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ283Ra01 Monoclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IP.
PAQ283Ra01 Polyclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IF.
Assay Kits CLQ283Ra01 CLIA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) CLIA assay for Antigen Detection
ELQ283Ra01 ELISA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ283Ca01 Recombinant Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ283Ca01 Monoclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IP.
PAQ283Ca01 Polyclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IF.
Assay Kits CLQ283Ca01 CLIA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) CLIA assay for Antigen Detection
ELQ283Ca01 ELISA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ283Po01 Recombinant Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ283Po01 Monoclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IP.
PAQ283Po01 Polyclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IF.
Assay Kits CLQ283Po01 CLIA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) CLIA assay for Antigen Detection
ELQ283Po01 ELISA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ283Bo01 Recombinant Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ283Bo01 Monoclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IP.
PAQ283Bo01 Polyclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IF.
Assay Kits CLQ283Bo01 CLIA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) CLIA assay for Antigen Detection
ELQ283Bo01 ELISA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ283Rb01 Recombinant Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ283Rb01 Monoclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IP.
PAQ283Rb01 Polyclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IF.
Assay Kits CLQ283Rb01 CLIA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) CLIA assay for Antigen Detection
ELQ283Rb01 ELISA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ283Mo01 Recombinant Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ283Mo01 Monoclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IP.
PAQ283Mo01 Polyclonal Antibody to Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) WB; IHC; ICC; IF.
Assay Kits CLQ283Mo01 CLIA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) CLIA assay for Antigen Detection
ELQ283Mo01 ELISA Kit for Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"A novel family of cell surface receptors with tyrosine kinase-like domain."
J. Biol. Chem. 267:26181-26190(1992) [PubMed] [Europe PMC] [Abstract]

"Human neural tissues express a truncated Ror1 receptor tyrosine kinase, lacking both extracellular and transmembrane domains."
Oncogene 13:1555-1559(1996) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

"Patterns of somatic mutation in human cancer genomes."
Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]